Impact of incisional negative pressure wound therapy on perineal wound healing after abdominoperineal rectum extirpation. 2017

Armin Wiegering, and Ulrich A Dietz, and Caroline Corteville, and Lars Plaßmeier, and Christian Jurowich, and Christoph-Thomas Germer, and Katica Krajinovic
Department of General, Visceral, Vascular and Pediatric Surgery, University Hospital, Julius-Maximilians-University, University of Wuerzburg, Oberduerrbacherstr.6, 97080, Wuerzburg, Germany. wiegering_a@ukw.de.

BACKGROUND Perineal wound healing disorders are one of the major complications following abdominoperineal rectum extirpation. RESULTS We evaluated the impact of an "incisional negative pressure wound therapy" (iNPWT) system after abdominoperineal rectum extirpation in six patients. All patients had a neoadjuvant radiochemotherapy with 50.4 Gy and 5-FU. Five of the six patients (83%) experienced complication-free healing of the perineal wound after 5 to 12 days of iNPWT. One patient developed a wound healing disorder 8 days after abdominoperineal rectum extirpation during current iNPWT. CONCLUSIONS Use of an iNPWT system can be of favor after abominoperineal rectum extirpation.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010502 Perineum The body region lying between the genital area and the ANUS on the surface of the trunk, and to the shallow compartment lying deep to this area that is inferior to the PELVIC DIAPHRAGM. The surface area is between the VULVA and the anus in the female, and between the SCROTUM and the anus in the male. Perineums
D012007 Rectum The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL. Rectums
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000005 Abdomen That portion of the body that lies between the THORAX and the PELVIS. Abdomens
D013524 Surgical Flaps Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region. Island Flap,Island Flaps,Flap, Surgical,Flaps, Surgical,Pedicled Flap,Surgical Flap,Flap, Island,Flap, Pedicled,Flaps, Island,Flaps, Pedicled,Pedicled Flaps
D014945 Wound Healing Restoration of integrity to traumatized tissue. Healing, Wound,Healings, Wound,Wound Healings
D054843 Negative-Pressure Wound Therapy The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing. Negative-Pressure Dressings,Topical Negative-Pressure Therapy,Vacuum-Assisted Closure,Closure, Vacuum-Assisted,Closures, Vacuum-Assisted,Dressing, Negative-Pressure,Dressings, Negative-Pressure,Negative Pressure Dressings,Negative Pressure Wound Therapy,Negative-Pressure Dressing,Negative-Pressure Therapies, Topical,Negative-Pressure Therapy, Topical,Negative-Pressure Wound Therapies,Therapies, Negative-Pressure Wound,Therapies, Topical Negative-Pressure,Therapy, Negative-Pressure Wound,Therapy, Topical Negative-Pressure,Topical Negative Pressure Therapy,Topical Negative-Pressure Therapies,Vacuum Assisted Closure,Vacuum-Assisted Closures,Wound Therapies, Negative-Pressure,Wound Therapy, Negative-Pressure

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