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Very late activation antigen on synovial fluid T cells from patients with rheumatoid arthritis and other rheumatic diseases. 1989
A Laffon, and
F Sánchez-Madrid, and
M Ortíz de Landázuri, and
A Jiménez Cuesta, and
A Ariza, and
C Ossorio, and
P Sabando
Section of Rheumatology, Hospital de la Princesa, Universidad Autónoma de Madrid, Spain.
We used flow cytometry and immunoprecipitation techniques to study the expression of the activation molecules transferrin receptor, interleukin-2 receptor, HLA-DR, and very late activation antigen 1 (VLA-1) on purified T lymphocytes from peripheral blood and synovial fluid of 9 patients with rheumatoid arthritis and 7 patients with other rheumatic diseases. We found a T cell subset bearing VLA-1 in synovial fluid from 8 rheumatoid arthritis patients and 4 patients with other rheumatic diseases. VLA-1 was not found in peripheral blood T lymphocytes from either group.
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