-transparent.png){kind=logo}
An ultrastructural study of life cycle stages of Pneumocystis carinii in infected rat lungs in situ was undertaken utilizing 8 different modes of fixation. Three of the fixatives employed gave good fixation of cysts and intracystic bodies, but for the trophic forms fixation was only fair. Both the trophic forms and intracystic bodies have nuclear pores. The mitochondria of the organism have cristae that appear lamellar. One of the fixation modes revealed a thin, electron-dense layer on the outer surface of the cell wall, a "fuzzy coat" that had not been described previously. This material appears to mediate tight adhesion of trophic forms with other trophic forms, cysts, and with pneumocytes of the lung alveolus.
J J Ruffolo, and
M T Cushion, and
P D Walzer
February 1969,
The American journal of pathology,
J J Ruffolo, and
M T Cushion, and
P D Walzer
January 1991,
The Journal of protozoology,
J J Ruffolo, and
M T Cushion, and
P D Walzer
January 2013,
PloS one,
J J Ruffolo, and
M T Cushion, and
P D Walzer
January 1985,
The Journal of infectious diseases,
J J Ruffolo, and
M T Cushion, and
P D Walzer
January 1989,
The Journal of protozoology,
J J Ruffolo, and
M T Cushion, and
P D Walzer
March 1977,
Zeitschrift fur Parasitenkunde (Berlin, Germany),
J J Ruffolo, and
M T Cushion, and
P D Walzer
December 1998,
Seminars in respiratory infections,
J J Ruffolo, and
M T Cushion, and
P D Walzer
February 1996,
The Journal of parasitology,
J J Ruffolo, and
M T Cushion, and
P D Walzer
February 2006,
Saudi medical journal,
J J Ruffolo, and
M T Cushion, and
P D Walzer
December 1998,
Investigacion clinica,
