[Patho-anatomic changes in rotaviral gastroenteritis in children]. 1989

A V Novikova, and E A Smirnov, and V M Shebekova, and L V Feklisova, and N M Gracheva, and T A Blokhina, and A P Besshaposhnikova, and Iu A Mikhaliuk, and A A Avakov

Two children (a 6-month-old girl and a 9-month boy) died from Rotavirus gastroenteritis as evidenced by virological, electron microscopic, and immune fluorescence studies of intestinal tissue. Histological and morphometric examinations of the small intestine revealed acute diffuse enteritis with enlarged and shortened villi, infiltration of intrinsic plates with lymphocytes, plasma cells and macrophages, enhanced mitotic activity of epitheliocytes and their increased lymphocyte-induced infiltration. The hepatic tissue showed central lobular fatty infiltration. The above changes should be regarded as manifestations of Rotavirus infection. Pneumonia detected in one of the children had been caused by influenza infection.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007421 Intestine, Small The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM. Small Intestine,Intestines, Small,Small Intestines
D005759 Gastroenteritis INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER. Gastroenteritides
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012400 Rotavirus Infections Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice. Infection, Rotavirus,Infections, Rotavirus,Rotavirus Infection

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