BIOMAT Database Logo BIOMAT Database Logo

Mild induced hypothermia for patients with severe traumatic brain injury after decompressive craniectomy. 2017

Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou City, Guangdong Province, China; Department of Neurosurgery, Tenth Affiliated Hospital, Guangxi Medical University, Guangdong Province, China.

To evaluate the efficacy and safety of mild induced hypothermia for intracranial hypertension in patients with traumatic brain injury after decompressive craniectomy. A total of 60 adults with intracranial pressure (ICP) of more than 20 mm Hg after decompressive craniectomy were randomly assigned to standard care (control group) or hypothermia (32°C-35°C) plus standard care. Then, ICP, cerebral perfusion pressure, Glasgow Outcome Scale score, and complications were assessed. There was a significant difference in ICP and cerebral perfusion pressure between the 2 groups. Favorable outcomes occurred in 12 (40.0%) and 7 (36.5%) patients in the hypothermia and control groups, respectively (P=.267). Kaplan-Meier curves revealed a marked difference in survival between the hypothermia and control groups (P=.032). There were significant differences in pulmonary infection and electrolyte disorders between the hypothermia and control groups (P=.038 and .033, respectively). Mild induced hypothermia can reduce intracranial hypertension after decompressive craniectomy, decreasing patient mortality. Hypothermia should be considered one of the main treatments for intracranial hypertension after decompressive craniectomy in patients with traumatic brain injury.

UI MeSH Term Description Entries
D007036 Hypothermia, Induced Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries. Induced Hypothermia,Mild Hypothermia, Induced,Moderate Hypothermia, Induced,Targeted Temperature Management,Therapeutic Hypothermia,Hypothermia, Therapeutic,Induced Mild Hypothermia,Induced Mild Hypothermias,Induced Moderate Hypothermia,Induced Moderate Hypothermias,Mild Hypothermias, Induced,Moderate Hypothermias, Induced,Targeted Temperature Managements
D007427 Intracranial Pressure Pressure within the cranial cavity. It is influenced by brain mass, the circulatory system, CSF dynamics, and skull rigidity. Intracerebral Pressure,Subarachnoid Pressure,Intracerebral Pressures,Intracranial Pressures,Pressure, Intracerebral,Pressure, Intracranial,Pressure, Subarachnoid,Pressures, Intracerebral,Pressures, Intracranial,Pressures, Subarachnoid,Subarachnoid Pressures
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011312 Pressure A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Pressures
D004311 Double-Blind Method A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000070642 Brain Injuries, Traumatic A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain. Trauma, Brain,Traumatic Brain Injury,Encephalopathy, Traumatic,Injury, Brain, Traumatic,TBI (Traumatic Brain Injury),TBIs (Traumatic Brain Injuries),Traumatic Encephalopathy,Brain Injury, Traumatic,Brain Trauma,Brain Traumas,Encephalopathies, Traumatic,TBI (Traumatic Brain Injuries),Traumas, Brain,Traumatic Brain Injuries,Traumatic Encephalopathies
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Severe traumatic brain injury managed with decompressive craniectomy.
January 2012, Nigerian journal of clinical practice,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Outcomes after decompressive craniectomy for severe traumatic brain injury in children.
November 2006, Journal of neurosurgery,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Posttraumatic Hydrocephalus after Decompressive Craniectomy in 126 Patients with Severe Traumatic Brain Injury.
March 2016, Journal of neurological surgery. Part A, Central European neurosurgery,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Decompressive craniectomy for severe traumatic brain injury patients with fixed dilated pupils.
January 2015, Therapeutics and clinical risk management,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Prognosis for severe traumatic brain injury patients treated with bilateral decompressive craniectomy.
January 2010, Acta neurochirurgica. Supplement,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Editorial: Severe traumatic brain injury and decompressive craniectomy.
November 2015, Journal of neurosurgery. Pediatrics,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Decompressive craniectomy for traumatic brain injury.
July 2011, The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Delayed neurological recovery after decompressive craniectomy for severe nonpenetrating traumatic brain injury.
November 2011, Critical care medicine,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
Early autologous cranioplasty after decompressive hemi-craniectomy for severe traumatic brain injury.
December 2015, JPMA. The Journal of the Pakistan Medical Association,
Chunhai Tang, and Yun Bao, and Min Qi, and Lizhi Zhou, and Fan Liu, and Jian Mao, and Qingmei Lei, and Songtao Qi, and Binghui Qiu
[Which indication for decompressive craniectomy after severe traumatic brain injury in adult?].
June 2004, Annales francaises d'anesthesie et de reanimation,
Copied contents to your clipboard!