Carcinogenic effects in rat progeny exposed perinatally to radionuclides. 1989

Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
Institute of Biophysics, Ministry of Health, Moscow, USSR.

The distribution of two transuranic elements, plutonium and americium, in pregnant rats and in their fetuses, and the carcinogenic effects seen in progeny exposed perinatally are discussed. The appearance of malignant tumours in the liver and skeleton corresponds to the pattern of deposition of these radionuclides in the body.

UI MeSH Term Description Entries
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D009381 Neoplasms, Radiation-Induced Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation. Radiation-Induced Cancer,Cancer, Radiation-Induced,Radiation-Induced Neoplasms,Cancer, Radiation Induced,Cancers, Radiation-Induced,Neoplasm, Radiation-Induced,Neoplasms, Radiation Induced,Radiation Induced Cancer,Radiation Induced Neoplasms,Radiation-Induced Cancers,Radiation-Induced Neoplasm
D011005 Plutonium A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, and atomic number 94. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011297 Prenatal Exposure Delayed Effects The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH. Delayed Effects, Prenatal Exposure,Late Effects, Prenatal Exposure
D011919 Rats, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D005260 Female Females
D000576 Americium A completely man-made radioactive actinide with atomic symbol Am, and atomic number 95. Its valence can range from +3 to +6. Because of its nonmagnetic ground state, it is an excellent superconductor. It is also used in bone mineral analysis and as a radiation source for radiotherapy.
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000831 Animals, Newborn Refers to animals in the period of time just after birth. Animals, Neonatal,Animal, Neonatal,Animal, Newborn,Neonatal Animal,Neonatal Animals,Newborn Animal,Newborn Animals

Related Publications

Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
September 2015, Biomedical and environmental sciences : BES,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
July 2016, Toxicological sciences : an official journal of the Society of Toxicology,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
January 2005, Journal of applied toxicology : JAT,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
March 2014, Archives of toxicology,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
January 2014, Annali dell'Istituto superiore di sanita,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
January 2021, Chemosphere,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
January 2013, Neurotoxicology and teratology,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
November 1979, Cancer research,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
February 1971, Journal of the National Cancer Institute,
Moskalev YuI, and A M Lyaginskaya, and G A Zalikin, and P G Nisimov, and I B Romanova, and Korneev YeYu
July 2014, Epigenetics,
Copied contents to your clipboard!