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The clinical and histologic features of 26 cases of erythema induratum are reviewed. The characteristic cutaneous lesions on the legs of middle-aged women were violaceous, indurated nodules, 1 to 2 cm in diameter, which were painful, occasionally ulcerated, and could heal with scarring. The diagnosis was confirmed in all patients by a strongly positive Mantoux test result (1:10,000 dilution) and by clearing of lesions after antituberculosis therapy. The histologic features were varied but were predominantly those of a vasculitis with a paraseptal and lobular panniculitis. Although it was not possible to fulfill the required criteria for diagnosing tuberculosis in these lesions, we believe there is sufficient circumstantial evidence to support the hypothesis that erythema induratum is a true tuberculid.
M Rademaker, and
D G Lowe, and
D D Munro
October 1991,
Irish medical journal,
M Rademaker, and
D G Lowe, and
D D Munro
October 1964,
New York state journal of medicine,
M Rademaker, and
D G Lowe, and
D D Munro
November 1959,
Concours medical,
M Rademaker, and
D G Lowe, and
D D Munro
March 1960,
Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille,
M Rademaker, and
D G Lowe, and
D D Munro
July 2006,
The Journal of rheumatology,
M Rademaker, and
D G Lowe, and
D D Munro
September 1971,
Revista brasileira de medicina,
M Rademaker, and
D G Lowe, and
D D Munro
August 1981,
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,
M Rademaker, and
D G Lowe, and
D D Munro
January 1908,
Proceedings of the Royal Society of Medicine,
M Rademaker, and
D G Lowe, and
D D Munro
September 2000,
Annals of the Academy of Medicine, Singapore,
