Biomaterial Database

Alteration in pulmonary blood flow induced by cold exposure to the hand in progressive systemic sclerosis. 1989

K Yamauchi, and S Arimori

Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.

To determine whether pulmonary blood flow is altered by cold exposure to the hand, cold exposure was induced by immersion of the left hand in 7 degrees C water in 8 patients with progressive systemic sclerosis (PSS). Lung perfusion was measured by continuous infusion of 81M krypton into the right antecubital vein. Exposing the left hand to cold caused an 11 to 32% decrease in the pulmonary blood flow in all lung fields in 4 of 8 patients. After release of cold exposure, in one of the 4 patients demonstrating a decrease during cold exposure, pulmonary blood flow recovered, while it kept on a decrease in the remaining 3 patients. Physiological abnormalities of pulmonary blood flow in PSS have been shown as a quantitative change and a image.

UI	MeSH Term	Description	Entries
D007727	Krypton Radioisotopes	Unstable isotopes of krypton that decay or disintegrate emitting radiation. Kr atoms with atomic weights 74-77, 79, 81, 85, and 87-94 are radioactive krypton isotopes.	Radioisotopes, Krypton
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011652	Pulmonary Circulation	The circulation of the BLOOD through the LUNGS.	Pulmonary Blood Flow,Respiratory Circulation,Circulation, Pulmonary,Circulation, Respiratory,Blood Flow, Pulmonary,Flow, Pulmonary Blood,Pulmonary Blood Flows
D011658	Pulmonary Fibrosis	A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.	Alveolitis, Fibrosing,Idiopathic Diffuse Interstitial Pulmonary Fibrosis,Fibroses, Pulmonary,Fibrosis, Pulmonary,Pulmonary Fibroses,Alveolitides, Fibrosing,Fibrosing Alveolitides,Fibrosing Alveolitis
D011877	Radionuclide Imaging	The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.	Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D003080	Cold Temperature	An absence of warmth or heat or a temperature notably below an accustomed norm.	Cold,Cold Temperatures,Temperature, Cold,Temperatures, Cold
D005260	Female		Females
D006225	Hand	The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.	Hands