Biomaterial Database

[The use of anti-A, anti-B and anti-AB monoclonal antibodies in a blood transfusion center. Preliminary results]. 1989

C Micali, and D Samà

Centro Trasfusionale e Immunoematologico, Università di Messina.

The properties of the anti-A, anti-B and anti-AB monoclonal antibodies were investigated by comparing these with 3 polyclonal antibodies with particular emphasis on specificity, titre and take-up. The results obtained suggest that monoclonal antibodies are highly specific and possess a similar titre but a superior take-up capacity to the polyclonal antibodies. It is concluded that they will be extremely valuable in immunohaematology laboratories.

UI	MeSH Term	Description	Entries
D007518	Isoantibodies	Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.	Alloantibodies
D001788	Blood Grouping and Crossmatching	Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.	Blood Typing,Crossmatching, Blood,Blood Grouping,Blood Crossmatching,Grouping, Blood,Typing, Blood
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000017	ABO Blood-Group System	The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.	ABH Blood Group,ABO Blood Group,ABO Factors,Blood Group H Type 1 Antigen,H Blood Group,H Blood Group System,ABO Blood Group System,Blood Group, ABH,Blood Group, ABO,Blood Group, H,Blood-Group System, ABO,Factors, ABO,System, ABO Blood-Group
D000911	Antibodies, Monoclonal	Antibodies produced by a single clone of cells.	Monoclonal Antibodies,Monoclonal Antibody,Antibody, Monoclonal