Radiocaesium metabolism in pregnant ewes and their progeny. 1989

C M Vandecasteele, and M van Hees, and J P Culot, and J Vankerkom
Radiation Protection Department, CEN/SCK, Mol, Belgium.

Pregnant ewes have been chronically contaminated during pregnancy and lactation with Cs-134 administered as CsCl in the food. Plateau concentrations in excreta and blood were reached after about 20 d of contamination. At delivery, the contamination levels in lamb's tissue were lower than those in the corresponding organs from an ewe; they increased rapidly as the lambs received milk from their contaminated dam, up to higher levels than in ewes. The transfer coefficient were estimated in various tissues from an ewe slaughtered at delivery (muscles 0.57 d/kg, kidneys 0.50 d/kg, liver 0.33 d/kg, blood 0.02 d/kg) and milk (0.09 d/l). During the decontamination phase, the radioactivity was excreted from the ewe's body according to a two exponential pattern with half-times of about 1.3 and 20 d. The retention in muscles, kidneys and liver from the ewes was characterised by two compartments with longer half-times of 2.3 to 2.9 d and 123 to 174 d respectively. The contamination levels in organs from lambs separated from their dam 3 days after birth and fed uncontaminated artificial milk decreased with a global half-time of about 10 d.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D007700 Kinetics The rate dynamics in chemical or physical systems.
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D008892 Milk The off-white liquid secreted by the mammary glands of humans and other mammals. It contains proteins, sugar, lipids, vitamins, and minerals. Cow Milk,Cow's Milk,Milk, Cow,Milk, Cow's
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009688 Nuclear Reactors Devices containing fissionable material in sufficient quantity and so arranged as to be capable of maintaining a controlled, self-sustaining NUCLEAR FISSION chain reaction. They are also known as atomic piles, atomic reactors, fission reactors, and nuclear piles, although such names are deprecated. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Nuclear Reactor,Reactor, Nuclear,Reactors, Nuclear
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011270 Pregnancy, Animal The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH. Animal Pregnancies,Animal Pregnancy,Pregnancies, Animal
D011847 Radioactive Fallout The material that descends to the earth or water well beyond the site of a surface or subsurface nuclear explosion. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed) Fallout, Radioactive,Fallouts, Radioactive,Radioactive Fallouts

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