Biomaterial Database

[Ultrasonic medicinal aerosols in multimodal treatment of acute surgical diseases of the organs of the abdominal cavity]. 1989

I S Gadzhiev

Microbiologic studies have shown that ultrasonic aerosol treatment of E. coli reference culture with 0.02% furacillin solution for 3 min reduces its survival rate by 2 orders (240-fold). Exposure to low-energy ultrasound increases 7-fold the antibacterial activity of furacillin solution. Experiments have demonstrated that 99mTc ionized particles diffusion via cadaver peritoneum is enhanced more than 5 times if Tc solution is spread via ultrasonic aerosol. A method for ultrasonic aerosol treatment of infected abdominal cavity has been developed. Clinical trials of the method have been carried out: it has been employed in multiple-modality treatment of acute surgical diseases of the abdominal organs in 6 patients and of postoperative peritonitis in 15 patients, as well as for the prevention of purulent complications after extensive abdominal surgery in 4 patients.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009583	Nitrofurazone	A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS.	Nitrofural,Furacilin,Furacillin,Furacin,Nitrofurazone, Calcium (2:1) Salt
D010538	Peritonitis	INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.	Primary Peritonitis,Secondary Peritonitis,Peritonitis, Primary,Peritonitis, Secondary
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D003131	Combined Modality Therapy	The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.	Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000006	Abdomen, Acute	A clinical syndrome with acute abdominal pain that is severe, localized, and rapid in onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases.	Abdomens, Acute,Acute Abdomen,Acute Abdomens
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000336	Aerosols	Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.	Aerosol