BIOMAT Database Logo BIOMAT Database Logo

[The complement system--a fascinating biological cascade. 2--clinical aspects]. 1989

T E Mollnes

Knowledge about the complement system has increased considerably the recent years. Research in the field of activation and regulation of the system has contributed to a more dynamic conception of how the system functions under physiological and pathophysiological conditions. In the first paper, the author considered some important physiological mechanisms. In this paper, he discusses some clinical aspects of complement deficiencies and pathological complement activation. He briefly reviews relevant laboratory tests for clinical evaluation of complement, with particular emphasis on interpretation of the results.

UI MeSH Term Description Entries
D007239 Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. Infection,Infection and Infestation,Infections and Infestations,Infestation and Infection,Infestations and Infections
D003165 Complement System Proteins Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY). Complement Proteins,Complement,Complement Protein,Hemolytic Complement,Complement, Hemolytic,Protein, Complement,Proteins, Complement,Proteins, Complement System
D003167 Complement Activation The sequential activation of serum COMPLEMENT PROTEINS to create the COMPLEMENT MEMBRANE ATTACK COMPLEX. Factors initiating complement activation include ANTIGEN-ANTIBODY COMPLEXES, microbial ANTIGENS, or cell surface POLYSACCHARIDES. Activation, Complement,Activations, Complement,Complement Activations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001327 Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. Autoimmune Disease,Disease, Autoimmune,Diseases, Autoimmune

Related Publications

T E Mollnes
[The complement system: a fascinating biological chain of events].
March 1993, Medicina clinica,
T E Mollnes
[Clinical aspects of the complement system].
July 2006, Rinsho byori. The Japanese journal of clinical pathology,
T E Mollnes
[Complement: function. Biological significance and clinical aspects (author's transl)].
November 1979, MMW, Munchener medizinische Wochenschrift,
T E Mollnes
[Disorders of the complement system: clinical aspects and diagnosis].
March 1994, Deutsche medizinische Wochenschrift (1946),
T E Mollnes
[Immunogenetics: the clinical and population aspects. The complement system (4.)].
January 1991, Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna,
T E Mollnes
The biological role of the complement system and the clinical importance of complement measurements.
January 1978, Haematologia,
T E Mollnes
The complement system: history, pathways, cascade and inhibitors.
June 2012, European journal of microbiology & immunology,
T E Mollnes
New biological activity following intravascular activation of the complement cascade.
June 1974, Nature,
T E Mollnes
[Complement system: biological functions].
May 1981, Boletin de la Asociacion Medica de Puerto Rico,
T E Mollnes
An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system.
January 2021, Bulletin of the National Research Centre,
Copied contents to your clipboard!