Biomaterial Database

Intraoperative Margin Assessment in Early Oral Squamous Cell Carcinoma. 2017

Simion I Chiosea

Department of Pathology, Presbyterian University Hospital, University of Pittsburgh Medical Center, A610.3, 200 Lothrop Street, Pittsburgh, PA 15213, USA. Electronic address: chioseasi@upmc.edu.

The surgical method of margin sampling affects local control, pathologists' approach to margin sampling, and clarity of pathology reports. Studies have shown that exclusive reliance on tumor bed margins is associated with worse local control and should be avoided. En bloc resections and margins obtained from the resection specimen remain the "gold standard." Successful surgical treatment of early carcinomas of the oral cavity relies on close cooperation between surgeons and pathologists on issues of specimen orientation and margin sampling.

UI	MeSH Term	Description	Entries
D007430	Intraoperative Care	Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.	Care, Intraoperative
D009062	Mouth Neoplasms	Tumors or cancer of the MOUTH.	Cancer of Mouth,Mouth Cancer,Oral Cancer,Oral Neoplasms,Cancer of the Mouth,Neoplasms, Mouth,Neoplasms, Oral,Cancer, Mouth,Cancer, Oral,Cancers, Mouth,Cancers, Oral,Mouth Cancers,Mouth Neoplasm,Neoplasm, Mouth,Neoplasm, Oral,Oral Cancers,Oral Neoplasm
D002294	Carcinoma, Squamous Cell	A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	Carcinoma, Epidermoid,Carcinoma, Planocellular,Carcinoma, Squamous,Squamous Cell Carcinoma,Carcinomas, Epidermoid,Carcinomas, Planocellular,Carcinomas, Squamous,Carcinomas, Squamous Cell,Epidermoid Carcinoma,Epidermoid Carcinomas,Planocellular Carcinoma,Planocellular Carcinomas,Squamous Carcinoma,Squamous Carcinomas,Squamous Cell Carcinomas
D005629	Frozen Sections	Thinly cut sections of frozen tissue specimens prepared with a cryostat or freezing microtome.	Frozen Section,Section, Frozen,Sections, Frozen
D005927	Glossectomy	Partial or total surgical excision of the tongue. (Dorland, 28th ed)	Glossectomies
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072662	Margins of Excision	The edges of tissue removed in a surgery for assessment of the effectiveness of a surgical procedure in achieving the local control of a neoplasm and the adequacy of tumor removal. When the margin is negative or not involved by tumor (e.g., CANCER) it suggests all of the tumor has been removed by the surgery.	Negative Surgical Margins,Positive Surgical Margins,Resection Margin,Surgical Margins,Tumor-Free Margins,Excision Margin,Excision Margins,Margin, Resection,Margin, Surgical,Margin, Tumor-Free,Margins, Resection,Margins, Surgical,Margins, Tumor-Free,Negative Surgical Margin,Positive Surgical Margin,Resection Margins,Surgical Margin,Surgical Margin, Negative,Surgical Margin, Positive,Surgical Margins, Negative,Surgical Margins, Positive,Tumor Free Margins,Tumor-Free Margin
D013048	Specimen Handling	Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.	Specimen Collection,Collection, Specimen,Collections, Specimen,Handling, Specimen,Handlings, Specimen,Specimen Collections,Specimen Handlings