Biomaterial Database

[Curettage of giant cell tumors with temporary implantation of bone cement]. 1989

A Härle, and P Wuisman

Orthop. Universitätsklinik, Münster.

Curettage with simultaneous bone transplantation is followed by a recurrence rate of 20-60%. In a follow-up of own cases up to 36 years after treatment recurrence was roughly 50%. In the last 10 years we changed to on other treatment procedure, namely optical controlled curettage with temporary cementation. To prevent further damage to the preexisting destabilization of the periarticular cortical bone, tumor excision is done through a small bone window, using a cold lighted mirror to achieve complete curettage. The cavity is then filled with bone cement, which is left in place for 3 months. When at that time there are no signs for tumor persistence, the cement is removed and bone reconstruction performed. An analysis of 17 cases treated this way showed a clearly smaller recurrence rate of 6%; this difference was statistically significant when applying the Kaplan-Meier test.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009364	Neoplasm Recurrence, Local	The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.	Local Neoplasm Recurrence,Local Neoplasm Recurrences,Locoregional Neoplasm Recurrence,Neoplasm Recurrence, Locoregional,Neoplasm Recurrences, Local,Recurrence, Local Neoplasm,Recurrence, Locoregional Neoplasm,Recurrences, Local Neoplasm,Locoregional Neoplasm Recurrences,Neoplasm Recurrences, Locoregional,Recurrences, Locoregional Neoplasm
D001843	Bone Cements	Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.	Bone Cement,Bone Glues,Bone Pastes,Bone Glue,Bone Paste,Cement, Bone,Cements, Bone,Glue, Bone,Glues, Bone,Paste, Bone,Pastes, Bone
D001859	Bone Neoplasms	Tumors or cancer located in bone tissue or specific BONES.	Bone Cancer,Cancer of Bone,Cancer of the Bone,Neoplasms, Bone,Bone Neoplasm,Neoplasm, Bone
D005260	Female		Females
D005266	Femoral Neoplasms	New abnormal growth of tissue in the FEMUR.	Femoral Neoplasm,Neoplasm, Femoral,Neoplasms, Femoral
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005870	Giant Cell Tumors	Tumors of bone tissue or synovial or other soft tissue characterized by the presence of giant cells. The most common are giant cell tumor of tendon sheath and GIANT CELL TUMOR OF BONE.	Cell Tumor, Giant,Cell Tumors, Giant,Giant Cell Tumor,Tumor, Giant Cell,Tumors, Giant Cell
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths