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Two patients with extensive necrotizing otitis externa have been treated by hyperbaric oxygenation. One patient had facial nerve palsy and the other suffered from skull base involvement. Due to severe side effects, the preferred combined intravenous antibiotic therapy was changed to monotherapy in one case and completely withdrawn in the second. This was done before the commencement of hyperbaric oxygenation, while the necrotizing infection was still active. Hyperbaric oxygenation therapy was followed by complete resolution of the necrotizing otitis externa, which did not recur. The pathogenesis of the disease and mechanisms by which hyperbaric oxygenation might be of benefit are described. We conclude that hyperbaric oxygenation should be considered as adjuvant therapy for necrotizing otitis externa whenever a therapeutic pressure chamber is available.
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
April 1990,
Nederlands tijdschrift voor geneeskunde,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
July 2019,
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
January 1991,
Otolaryngologia polska = The Polish otolaryngology,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
September 2008,
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
September 2011,
Diving and hyperbaric medicine,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
December 2010,
Diving and hyperbaric medicine,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
December 2010,
Diving and hyperbaric medicine,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
March 1987,
Ceskoslovenska otolaryngologie,
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
March 2019,
Internal medicine (Tokyo, Japan),
A Shupak, and
E Greenberg, and
R Hardoff, and
C Gordon, and
Y Melamed, and
W S Meyer
January 1977,
Duodecim; laaketieteellinen aikakauskirja,
