Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa. 1978

A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D008781 Methyltyrosines A group of compounds that are methyl derivatives of the amino acid TYROSINE.
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D009638 Norepinephrine Precursor of epinephrine that is secreted by the ADRENAL MEDULLA and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the LOCUS CERULEUS. It is also found in plants and is used pharmacologically as a sympathomimetic. Levarterenol,Levonorepinephrine,Noradrenaline,Arterenol,Levonor,Levophed,Levophed Bitartrate,Noradrenaline Bitartrate,Noradrénaline tartrate renaudin,Norepinephrin d-Tartrate (1:1),Norepinephrine Bitartrate,Norepinephrine Hydrochloride,Norepinephrine Hydrochloride, (+)-Isomer,Norepinephrine Hydrochloride, (+,-)-Isomer,Norepinephrine d-Tartrate (1:1),Norepinephrine l-Tartrate (1:1),Norepinephrine l-Tartrate (1:1), (+,-)-Isomer,Norepinephrine l-Tartrate (1:1), Monohydrate,Norepinephrine l-Tartrate (1:1), Monohydrate, (+)-Isomer,Norepinephrine l-Tartrate (1:2),Norepinephrine l-Tartrate, (+)-Isomer,Norepinephrine, (+)-Isomer,Norepinephrine, (+,-)-Isomer
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002230 Carbidopa An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself. Methyldopahydrazine,Carbidopa, (R)-Isomer,Carbidopa, (S)-Isomer,Lodosin,Lodosyn,MK-485,MK-486,MK 485,MK 486,MK485,MK486
D004298 Dopamine One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. Hydroxytyramine,3,4-Dihydroxyphenethylamine,4-(2-Aminoethyl)-1,2-benzenediol,Dopamine Hydrochloride,Intropin,3,4 Dihydroxyphenethylamine,Hydrochloride, Dopamine
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004357 Drug Synergism The action of a drug in promoting or enhancing the effectiveness of another drug. Drug Potentiation,Drug Augmentation,Augmentation, Drug,Augmentations, Drug,Drug Augmentations,Drug Potentiations,Drug Synergisms,Potentiation, Drug,Potentiations, Drug,Synergism, Drug,Synergisms, Drug

Related Publications

A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
April 1989, Journal of hypertension,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
January 2023, Journal of the science of food and agriculture,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
December 1993, European journal of pharmacology,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
November 1972, Archives internationales de pharmacodynamie et de therapie,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
May 1992, European journal of pharmacology,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
May 1994, Bioscience, biotechnology, and biochemistry,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
January 1985, Arzneimittel-Forschung,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
January 1982, Clinical and experimental hypertension. Part A, Theory and practice,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
December 2008, Biopharmaceutics & drug disposition,
A Scriabine, and C T Ludden, and C S Sweet, and C C Porter, and E H Ulm, and C A Stone, and C J Watkins, and R J Wurtman, and B L Cronin
June 1989, Hypertension (Dallas, Tex. : 1979),
Copied contents to your clipboard!