RETRACTED: Protective effects of total flavonoids in Caragana against hypoxia/reoxygenation-induced injury in human brain microvascular endothelial cells. 2017

Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
Guiyang College of Traditional Chinese Medicine, Guiyang, 550025, PR China.

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier. Concern was raised about the reliability of the Transwell assay images shown in Figure 4A, which appear to contain similar features to those found in other publications, as detailed here: https://pubpeer.com/publications/FE1B7461C358F48E6838BF1622C291; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. An additional suspected image duplication within Figure 5A was also identified. The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.

UI MeSH Term Description Entries
D009389 Neovascularization, Pathologic A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions. Angiogenesis, Pathologic,Angiogenesis, Pathological,Neovascularization, Pathological,Pathologic Angiogenesis,Pathologic Neovascularization,Pathological Angiogenesis,Pathological Neovascularization
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002448 Cell Adhesion Adherence of cells to surfaces or to other cells. Adhesion, Cell,Adhesions, Cell,Cell Adhesions
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002465 Cell Movement The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell. Cell Migration,Locomotion, Cell,Migration, Cell,Motility, Cell,Movement, Cell,Cell Locomotion,Cell Motility,Cell Movements,Movements, Cell
D002470 Cell Survival The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability. Cell Viability,Cell Viabilities,Survival, Cell,Viabilities, Cell,Viability, Cell
D005419 Flavonoids A group of phenyl benzopyrans named for having structures like FLAVONES. 2-Phenyl-Benzopyran,2-Phenyl-Chromene,Bioflavonoid,Bioflavonoids,Flavonoid,2-Phenyl-Benzopyrans,2-Phenyl-Chromenes,2 Phenyl Benzopyran,2 Phenyl Benzopyrans,2 Phenyl Chromene,2 Phenyl Chromenes
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012333 RNA, Messenger RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm. Messenger RNA,Messenger RNA, Polyadenylated,Poly(A) Tail,Poly(A)+ RNA,Poly(A)+ mRNA,RNA, Messenger, Polyadenylated,RNA, Polyadenylated,mRNA,mRNA, Non-Polyadenylated,mRNA, Polyadenylated,Non-Polyadenylated mRNA,Poly(A) RNA,Polyadenylated mRNA,Non Polyadenylated mRNA,Polyadenylated Messenger RNA,Polyadenylated RNA,RNA, Polyadenylated Messenger,mRNA, Non Polyadenylated
D015398 Signal Transduction The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. Cell Signaling,Receptor-Mediated Signal Transduction,Signal Pathways,Receptor Mediated Signal Transduction,Signal Transduction Pathways,Signal Transduction Systems,Pathway, Signal,Pathway, Signal Transduction,Pathways, Signal,Pathways, Signal Transduction,Receptor-Mediated Signal Transductions,Signal Pathway,Signal Transduction Pathway,Signal Transduction System,Signal Transduction, Receptor-Mediated,Signal Transductions,Signal Transductions, Receptor-Mediated,System, Signal Transduction,Systems, Signal Transduction,Transduction, Signal,Transductions, Signal

Related Publications

Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
November 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
January 2015, Evidence-based complementary and alternative medicine : eCAM,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
January 2020, Dose-response : a publication of International Hormesis Society,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
April 2023, Minerva medica,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
October 2021, The Journal of surgical research,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
January 2022, Human & experimental toxicology,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
October 2021, Neurotoxicity research,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
August 2010, Biochemistry and cell biology = Biochimie et biologie cellulaire,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
January 2019, American journal of translational research,
Qian-Song He, and Li Zhang, and Zi-Yuan Fan, and Guo Feng, and Fu-Jiang Wang, and Zheng-Qi Liu, and Ting Tang, and Shi-Xiang Kuang
January 2017, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology,
Copied contents to your clipboard!