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The case of a 61-year-old man, in whom heart transplantation was complicated by fatal gastrointestinal hemorrhage from duodenal ulcers 50 days after surgery, is described. Autopsy examination revealed extensive mucosal ulceration and hemorrhage into the bowel and peritoneal hemorrhage. Microscopy showed classical cytomegalovirus inclusions in clusters of cells in necrotic foci in the duodenum, lungs, and colon. This unusual case is the first reported example of cytomegalovirus-associated fatal gastrointestinal hemorrhage after heart transplantation. It is discussed in the context of the known features of the morbidity and mortality associated with cytomegalovirus infection in transplant patients.
N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
October 2012,
Transplant infectious disease : an official journal of the Transplantation Society,
N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
January 1970,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
January 2024,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
June 1978,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
January 1955,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
April 2003,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
January 1987,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
June 1972,
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N H Bramwell, and
R A Davies, and
A Koshal, and
G N Tse, and
W J Keon, and
V M Walley
June 1994,
The American journal of forensic medicine and pathology,
