Biomaterial Database

[A rare cause of chronic diarrhea: alpha heavy-chain disease]. 1987

M Westhoff-Bleck, and H Diedrich

Abteilung Diagnostische Radiologie, Medizinische Hochschule Hannover.

UI	MeSH Term	Description	Entries
D007137	Immunoglobulin alpha-Chains	The class of heavy chains found in IMMUNOGLOBULIN A. They have a molecular weight of approximately 58 kDa and contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to their Fc fragment constant region.	Ig alpha Chains,Immunoglobulins, alpha-Chain,Immunoglobulin alpha-Chain,alpha-Chain Immunoglobulins,alpha-Immunoglobulin Heavy Chain,alpha-Immunoglobulin Heavy Chains,Chains, Ig alpha,Heavy Chain, alpha-Immunoglobulin,Heavy Chains, alpha-Immunoglobulin,Immunoglobulin alpha Chain,Immunoglobulin alpha Chains,Immunoglobulins, alpha Chain,alpha Chain Immunoglobulins,alpha Chains, Ig,alpha Immunoglobulin Heavy Chain,alpha Immunoglobulin Heavy Chains,alpha-Chain, Immunoglobulin,alpha-Chains, Immunoglobulin
D008297	Male		Males
D002908	Chronic Disease	Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).	Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D003967	Diarrhea	An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.	Diarrheas
D006362	Heavy Chain Disease	A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.	Franklin Disease,gamma-Chain Disease,mu-Chain Disease,Franklin's Disease,Franklins Disease,Heavy Chain Diseases,gamma Chain Disease,gamma-Chain Diseases,mu Chain Disease,mu-Chain Diseases
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults