-transparent.png){kind=logo}
Prior exposure of immature rat testis to arginine vasopressin caused the testis refractory at 24 h in terms of ornithine decarboxylase activity. Arginine vasopressin caused desensitization both in Leydig cells and seminiferous tubules. Arginine vasopressin induced desensitization was found to be both time and dose-dependent. Arginine vasopressin desensitized testis was refractory to luteinizing hormone, follicle stimulating hormone, norepinephrine, dibutyryl cAMP, phorbol-myristate acetate and cholera toxin at 24 h. Arginine vasopressin desensitized testis showed recovery of response to norepinephrine at 48 h after the first injection. On the contrary arginine vasopressin could stimulate ornithine decarboxylase in luteinizing hormone desensitized testis. These results indicate that in arginine vasopressin desensitized testis the block is at post cAMP step which is common to both cAMP dependent and protein kinase C-diacylglycerol system in stimulating testicular ornithine decarboxylase.
B V Reddy, and
R Madhubala, and
P R Reddy
June 1980,
Life sciences,
B V Reddy, and
R Madhubala, and
P R Reddy
June 1989,
Endocrinology,
B V Reddy, and
R Madhubala, and
P R Reddy
May 2000,
Journal of neurochemistry,
B V Reddy, and
R Madhubala, and
P R Reddy
October 1984,
Canadian journal of physiology and pharmacology,
B V Reddy, and
R Madhubala, and
P R Reddy
February 1989,
The Journal of endocrinology,
B V Reddy, and
R Madhubala, and
P R Reddy
February 1989,
Biochemistry international,
B V Reddy, and
R Madhubala, and
P R Reddy
November 1985,
Biochemical and biophysical research communications,
B V Reddy, and
R Madhubala, and
P R Reddy
April 1995,
Hearing research,
B V Reddy, and
R Madhubala, and
P R Reddy
December 1985,
Biology of reproduction,
B V Reddy, and
R Madhubala, and
P R Reddy
January 1983,
Methods in enzymology,
