Biomaterial Database

Glomus jugulare tumours seen in Oxford 1960-1984. 1988

D J Cole

Department of Radiotherapy and Oncology, Churchill Hospital, Headington, Oxford.

A review of 14 cases of glomus jugulare tumour is presented. Patients with a long delay in diagnosis and those with cranial nerve palsies were found to have a poor prognosis. A dose response effect for local control was not observed with the radiation doses used. Three times weekly fractionation was well tolerated by adjacent normal tissues.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010236	Paraganglioma, Extra-Adrenal	A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the CAROTID BODY; GLOMUS JUGULARE; GLOMUS TYMPANICUM; AORTIC BODIES; and the female genital tract. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (From Stedman, 27th ed)	Chemodectoma,Paraganglioma, Nonchromaffin,Chemodectomas,Paraganglioma, Non-Chromaffin,Paragangliomas, Familial Nonchromaffin, 1,Extra-Adrenal Paraganglioma,Extra-Adrenal Paragangliomas,Non-Chromaffin Paraganglioma,Non-Chromaffin Paragangliomas,Nonchromaffin Paraganglioma,Nonchromaffin Paragangliomas,Paraganglioma, Extra Adrenal,Paraganglioma, Non Chromaffin,Paragangliomas, Extra-Adrenal,Paragangliomas, Non-Chromaffin,Paragangliomas, Nonchromaffin
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D004307	Dose-Response Relationship, Radiation	The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.	Dose Response Relationship, Radiation,Dose-Response Relationships, Radiation,Radiation Dose-Response Relationship,Radiation Dose-Response Relationships,Relationship, Radiation Dose-Response,Relationships, Radiation Dose-Response
D005260	Female		Females
D005925	Glomus Jugulare Tumor	A paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. It may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. It is not resectable but radiation therapy is effective. It regresses slowly, but permanent control is regularly achieved. (From Dorland, 27th ed; Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1603-4)	Glomus Jugulare Tumors,Glomus Tumors, Familial, 1,Paragangliomas 1,Paragangliomas, Familial, 1,Jugulare Tumor, Glomus,Tumor, Glomus Jugulare
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective