Early Results of Rheumatic Mitral Valve Repair. 2016

Giuseppe Petrone, and Panagiotis Theodoropoulos, and Prakash P Punjabi
Cardiothoracic Department, Hammersmith Hospital, Imperial College, London, UK. Electronic correspondence: dottpetrone@libero.it.

Mitral valve repair (MVr) in rheumatic heart disease (RHD) remains challenging. The present authors' surgical experience of MVr in 56 patients with RHD operated in between January 2011 and September 2014 is reported. Among the patients (mean age 32 ± 11 years), 11 were in NYHA functional class II, 32 in class III, and seven in class IV. An adequate or oversized autologous pericardial patch was sutured to extend the coaptating edge of both the anterior leaflet (in 18 patients) and the posterior leaflet (in 30 patients). Neochordae were implanted as needed (n = 43), and leaflet thinning (n = 13), commissurotomy (n = 15) and chordal splitting (n = 9) were also performed. A rigid annuloplasty ring was implanted in 32 patients, and in 24 patients a complete flexible annuloplasty ring made from pericardium, 4 mm Gore-Tex tube graft or a Dacron patch was constructed. Repair was not attempted in 16 patients, with replacement using a mechanical bileaflet prosthesis being considered the only option. Intraoperative post-repair transesophageal echocardiography demonstrated competency, with trivial mitral regurgitation (MR) up to grade I in all patients and a minimum coaptation depth ≥5 mm. There were no intraoperative or in-hospital deaths. Clinical and echocardiographic evaluations were performed up to six weeks after surgery, at which time 51 patients were in NYHA classes I-II and five were in class III. Residual mild MR up to grade I was identified in six patients. No recurrence of MR was observed in any of the patients, and no patients were reoperated on. The lack of adequate access to anticoagulation medication and monitoring, in addition to religious/cultural bias to the type of prosthetic valve used in low-income countries, necessitates an increase in the numbers of rheumatic MVr.

UI MeSH Term Description Entries
D008297 Male Males
D008943 Mitral Valve The valve between the left atrium and left ventricle of the heart. Bicuspid Valve,Bicuspid Valves,Mitral Valves,Valve, Bicuspid,Valve, Mitral,Valves, Bicuspid,Valves, Mitral
D005260 Female Females
D006349 Heart Valve Diseases Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE). Heart Valvular Disease,Valvular Heart Diseases,Disease, Heart Valvular,Heart Disease, Valvular,Heart Valve Disease,Heart Valvular Diseases,Valve Disease, Heart,Valvular Disease, Heart,Valvular Heart Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012214 Rheumatic Heart Disease Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM. Bouillaud Disease,Bouillaud's Disease,Bouillauds Disease,Disease, Bouillaud,Disease, Bouillaud's,Disease, Rheumatic Heart,Diseases, Rheumatic Heart,Heart Disease, Rheumatic,Heart Diseases, Rheumatic,Rheumatic Heart Diseases
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D055815 Young Adult A person between 19 and 24 years of age. Adult, Young,Adults, Young,Young Adults
D058385 Cardiac Valve Annuloplasty A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annuli of HEART VALVES. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs. Annular Reduction, Cardiac Valve,Annular Repair, Cardiac Valve,Annulus Reduction, Cardiac Valve,Annulus Repair, Cardiac Valve,Cardiac Valve Annular Reduction,Cardiac Valve Annular Repair,Cardiac Valve Annulus Reduction,Cardiac Valve Annulus Repair,Cardiac Valve Annulus Shortening,Heart Valve Annular Repair,Heart Valve Annuloplasty,Heart Valve Annulus Repair,Valvular Annuloplasty,Annuloplasties, Cardiac Valve,Annuloplasties, Heart Valve,Annuloplasties, Valvular,Annuloplasty, Cardiac Valve,Annuloplasty, Heart Valve,Annuloplasty, Valvular,Cardiac Valve Annuloplasties,Heart Valve Annuloplasties,Valve Annuloplasties, Cardiac,Valve Annuloplasties, Heart,Valve Annuloplasty, Cardiac,Valve Annuloplasty, Heart,Valvular Annuloplasties

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