Biomaterial Database

[The Evaluation of Left Ventricular Diastolic Function by Echocardiography in Patients With Preserved Ejection Fraction]. 2017

M N Alekhin, and A M Grishin, and O A Petrova

Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia.

OBJECTIVE to compare non-invasive evaluation of left ventricular (LV) diastolic function (DF) by echocardiography using algorithms of the 2009 and 2016 American Society of Echocardiography (ASE)/European Association of Echocardiography (EAE, now European Association of Cardiovascular Imaging [EACVI]) Recommendations. METHODS The study included 100 patients with sinus rhythm and preserved left ventricular (LV) ejection fraction (EF). In all patients LV DF was assessed using both algorithms. In accordance with the ASE/EAE 2009 algorithm pulsed-wave tissue Doppler early diastolic velocity (e velocity) at lateral and septal basal regions of mitral annulus, as well as left atrial maximum volume index were evaluated. In accordance with the ASE/EACVI 2016 algorithm for judging the presence of LV diastolic dysfunction (DD), in addition to the two above-described criteria, E/e ratio and peak velocity of tricuspid regurgitation were analyzed. In the presence of 1 and more or equal 3 criteria LVDF was classified as normal and DD, respectively. If 2 criteria were detected result was considered as indeterminate. RESULTS In 70% of patients in accordance with the ASE/EACVI 2016 algorithm DF was evaluated with 4 and in 100% - with 3 proposed criteria. The reason for using only 3 criteria was inadequate imaging of tricuspid regurgitation flow by continuous wave Doppler. Use of ASE/EACVI 2016 compared with the ASE/EAE 2009 algorithm in patients with normal LV EF led to a significant decrease of the number of patients with LV DD (13 vs. 27%, respectively; <0.05). The main reason for this redistribution was lowering of the cutoff value of annular e septal velocity from 8 (2009 algorithm) to 7 cm/sec (2016 algorithm). Frequency of indeterminate results with the use of 2016 algorithm was 2 times less than with the use of 2009 algorithm (15 vs. 36%, respectively; p<0.001). CONCLUSIONS In patients with preserved LVEF the use of ASE/EACVI 2016 algorithm led to redistribution of data of evaluation of LVDF by echocardiography towards reduction of the number of patients with LV DD and with indeterminate results.

UI	MeSH Term	Description	Entries
D008943	Mitral Valve	The valve between the left atrium and left ventricle of the heart.	Bicuspid Valve,Bicuspid Valves,Mitral Valves,Valve, Bicuspid,Valve, Mitral,Valves, Bicuspid,Valves, Mitral
D003971	Diastole	Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.	Diastoles
D004452	Echocardiography	Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.	Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000465	Algorithms	A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.	Algorithm
D013318	Stroke Volume	The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.	Ventricular Ejection Fraction,Ventricular End-Diastolic Volume,Ventricular End-Systolic Volume,Ejection Fraction, Ventricular,Ejection Fractions, Ventricular,End-Diastolic Volume, Ventricular,End-Diastolic Volumes, Ventricular,End-Systolic Volume, Ventricular,End-Systolic Volumes, Ventricular,Fraction, Ventricular Ejection,Fractions, Ventricular Ejection,Stroke Volumes,Ventricular Ejection Fractions,Ventricular End Diastolic Volume,Ventricular End Systolic Volume,Ventricular End-Diastolic Volumes,Ventricular End-Systolic Volumes,Volume, Stroke,Volume, Ventricular End-Diastolic,Volume, Ventricular End-Systolic,Volumes, Stroke,Volumes, Ventricular End-Diastolic,Volumes, Ventricular End-Systolic
D016277	Ventricular Function, Left	The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.	Left Ventricular Function,Function, Left Ventricular,Functions, Left Ventricular,Left Ventricular Functions,Ventricular Functions, Left
D018487	Ventricular Dysfunction, Left	A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.	LV Diastolic Dysfunction,LV Dysfunction,LV Systolic Dysfunction,Left Ventricular Diastolic Dysfunction,Left Ventricular Dysfunction,Left Ventricular Systolic Dysfunction,Diastolic Dysfunction, LV,Dysfunction, LV,Dysfunction, LV Diastolic,Dysfunction, LV Systolic,Dysfunction, Left Ventricular,LV Diastolic Dysfunctions,LV Dysfunctions,LV Systolic Dysfunctions,Left Ventricular Dysfunctions,Systolic Dysfunction, LV