BIOMAT Database Logo BIOMAT Database Logo

[Gangrene of the hand due to accidental intra-arterial injection of floxacilline: about a case]. 2016

Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
Service de Chirurgie Pédiatrique A, Départment des maladies de L'Enfant, CHU Mohammed VI, Université Cadi Ayyad, Marrakech, Maroc.

Floxacilline is a beta-lactam antibiotic of the penicillin class. In our context it is used to fight against infections caused by gram-positive bacteria, including staphylococcus aureus. However, floxacilline should be administered with great caution due to its possible side-effects. Our study reports the case of a 6-year old boy who underwent surgery for the treatment of a humeral fracture. The child was treated with injectable floxacilline following a suspected orthopaedic device infection 2 months after surgery. The day after starting antibiotic treatment, the child presented with acute ischemia of the right hand. Then, he was referred to us. Explorations objectified occlusion of the radial artery. The patient underwent relieving fasciotomy and received postoperative heparin. The evolution was marked by gangrene affecting the whole hand. The aim of our study was to educate caregivers about the risk of occurrence of this disastrous complication and about the measures to prevent it.

UI MeSH Term Description Entries
D007269 Injections, Intra-Arterial Delivery of drugs into an artery. Injections, Intraarterial,Intra-Arterial Injections,Intraarterial Injections,Injection, Intra-Arterial,Injection, Intraarterial,Injections, Intra Arterial,Intra Arterial Injections,Intra-Arterial Injection,Intraarterial Injection
D007511 Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. Ischemias
D008297 Male Males
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005436 Floxacillin Antibiotic analog of CLOXACILLIN. Flucloxacillin,Fluorochloroxacillin
D005734 Gangrene Death and putrefaction of tissue usually due to a loss of blood supply. Gangrenes
D006225 Hand The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb. Hands
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000071938 Fasciotomy Surgical incision on the FASCIA. It is used to decompress compartment pressure (e.g. in COMPARTMENT SYNDROMES; circumferential burns and extremity injuries) or to release contractures (e.g. in DUPUYTREN'S CONTRACTURE). Fasciectomy
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial

Related Publications

Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
[Gangrene of the hand and forearm following accidental intra-arterial injection of phenothiazines].
October 1976, Die Medizinische Welt,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
[Different treatments used in a case of gangrene due to accidental intra-arterial injection of methylphenidate (rilatine)].
January 1977, Anesthesie, analgesie, reanimation,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
Gangrene of the hand following intra-arterial injection.
January 1968, Anesthesia and analgesia,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
Gangrene of the hand following intra-arterial injection.
January 1967, Archives of surgery (Chicago, Ill. : 1960),
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
Digital gangrene after accidental intra-arterial injection of phenytoin (epanutin).
May 1992, The European journal of surgery = Acta chirurgica,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
[Gangrene of the fingers caused by accidental intra-arterial injection of diazepam].
June 1999, Deutsche medizinische Wochenschrift (1946),
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
[Finger gangrene caused by an accidental intra-arterial injection of ether].
November 1949, Prensa medica argentina,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
ACCIDENTAL INTRA-ARTERIAL DRUG INJECTION: A Case Report.
April 1997, Medical journal, Armed Forces India,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
Gangrene due to intra-arterial injection of drugs by drug addicts.
October 1972, Surgery,
Tarik Salama, and El Mohtadi Aghoutane, and Rédouane El Fezzazi
Accidental intra-arterial injection.
May 1978, Archives of disease in childhood,
Copied contents to your clipboard!