-transparent.png){kind=logo}
Human peripheral blood monocytes (M), incubated with opsonized zymosan particles (OPZ), lysed human erythrocyte (RBC) targets, as detected by a 51Cr release method. Conversely, cells derived in vitro from M (monocyte-derived macrophages, MDM) were ineffective. When added to the M-RBC system, MDM enhanced the lysis. The lysis by M and M plus MDM was prevented by catalase, azide and amino acids (alanine, taurine), consistent with the requirement for hypochlorous acid (HOCl). Moreover, MDM per se incapable of generating HOCl augmented the HOCl recovery from the M-RBC system. The results provide evidence for a previously unrecognized form of interaction between two distinct populations of mononuclear phagocytes.
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
October 2017,
Cellular & molecular immunology,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
February 2011,
Immunology,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
May 2014,
EMBO molecular medicine,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
October 2001,
Immunology and cell biology,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
September 1980,
Cellular immunology,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
May 2014,
EMBO molecular medicine,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
July 2000,
Immunology,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
January 2016,
PloS one,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
June 1997,
Transfusion science,
F Dallegri, and
A Ballestrero, and
G Frumento, and
R Goretti, and
F Patrone
September 1993,
Biochemical and biophysical research communications,
