Biomaterial Database

[Long term follow-up to identify the rectal potentially malignant nodules in female by digital rectal examination]. 2017

S S Wang, and J Y Zhou, and Z J Wang, and S R Su, and J Sun, and R G W Sharen

Department of Health Management Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Objective: To investigate the characteristics of the rectal potentially malignant nodules in female by digital rectal examination (DRE). Methods: Retrospectively, we collected the medical information and follow-up of rectal nodules cases diagnosed as benign by DRE during the health check-up in our hospital from Jan 2002 to Dec 2015. All nodules were recorded position, size, shape, hardness and mobility. Statistical analysis was performed to select the potentially malignant cases of postoperative pathological diagnosis and disappeared nodules followed up by DRE. Results: We followed up 190 cases with 195 nodules finally. Twenty-five cases were potentially malignant, including 14 (56.0%) of polyps, 9 (36.0%) neuroendocrine tumors, and 2 (8.0%) gastrointestinal stromal tumors. The sizes of the nodules were <1.0 cm of 23 (92%) cases, among them 12 (48%) cases were ≤0.5 cm, while 23 nodules (92%) were mobile.There were two cases of potentially malignancy in both groups with enlarged and unchanged modules.There were 69 cases of nodules disappeared during follow-up. The size of these nodules were <1.0 cm, 63(91.3%) cases ≤0.5 cm. while 32 (46.4%) were fixed. The univariate analysis showed that the detection rate of potentially malignant group was higher than that of disappeared group in age (t=-3.691, P<0.01), size (Z=-3.537, P<0.01) and mobility (χ(2)=13.315, P=0.001). On multivariate analysis, the risk of potentially malignant increased with age (OR=2.324, P=0.004) and the size (OR=1.537, P=0.003) of the nodules. The risk of fixed small nodules (OR=0.081, P=0.020) was lower than that of the mobile nodules. All the above differences were statistically significant. Conclusions: The risk of potential malignancy increased with age and the size of the nodule in female. The risk of fixed small nodules, which were regard as malignant, was lower than that of mobile nodules. Potential malignancy should exclude in small, enlarged or unchanged nodules during follow-up.

UI	MeSH Term	Description	Entries
D008279	Magnetic Resonance Imaging	Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.	Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D051517	Digital Rectal Examination	A physical examination in which the qualified health care worker inserts a lubricated, gloved finger of one hand into the RECTUM and may use the other hand to press on the lower ABDOMEN or pelvic area to palpate for abnormalities in the lower rectum, and nearby organs or tissues. The method is commonly used to check the lower rectum, the PROSTATE gland in men, and the UTERUS and OVARIES in women.	Rectal Palpation,Digital Rectal Examinations,Examination, Digital Rectal,Examinations, Digital Rectal,Palpation, Rectal,Palpations, Rectal,Rectal Examination, Digital,Rectal Examinations, Digital,Rectal Palpations