Incontinence: How do β3-adrenoceptor agonists work in the bladder? 2017

Yasuhiko Igawa, and Naoki Aizawa
Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

UI MeSH Term Description Entries
D001743 Urinary Bladder A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION. Bladder,Bladder Detrusor Muscle,Detrusor Urinae,Bladder Detrusor Muscles,Bladder, Urinary,Detrusor Muscle, Bladder,Detrusor Muscles, Bladder
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014549 Urinary Incontinence Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE. Incontinence, Urinary
D015415 Biomarkers Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, ENVIRONMENTAL EXPOSURE and its effects, disease diagnosis; METABOLIC PROCESSES; SUBSTANCE ABUSE; PREGNANCY; cell line development; EPIDEMIOLOGIC STUDIES; etc. Biochemical Markers,Biological Markers,Biomarker,Clinical Markers,Immunologic Markers,Laboratory Markers,Markers, Biochemical,Markers, Biological,Markers, Clinical,Markers, Immunologic,Markers, Laboratory,Markers, Serum,Markers, Surrogate,Markers, Viral,Serum Markers,Surrogate Markers,Viral Markers,Biochemical Marker,Biologic Marker,Biologic Markers,Clinical Marker,Immune Marker,Immune Markers,Immunologic Marker,Laboratory Marker,Marker, Biochemical,Marker, Biological,Marker, Clinical,Marker, Immunologic,Marker, Laboratory,Marker, Serum,Marker, Surrogate,Serum Marker,Surrogate End Point,Surrogate End Points,Surrogate Endpoint,Surrogate Endpoints,Surrogate Marker,Viral Marker,Biological Marker,End Point, Surrogate,End Points, Surrogate,Endpoint, Surrogate,Endpoints, Surrogate,Marker, Biologic,Marker, Immune,Marker, Viral,Markers, Biologic,Markers, Immune
D053201 Urinary Bladder, Overactive Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present. Overactive Detrusor,Bladder, Overactive,Overactive Bladder,Overactive Detrusor Function,Overactive Urinary Bladder,Detrusor Function, Overactive,Detrusor, Overactive
D058667 Adrenergic beta-3 Receptor Agonists Compounds that bind to and activate ADRENERGIC BETA-3 RECEPTORS. Adrenergic beta-3 Agonists,Adrenergic beta-3 Receptor Agonist,Adrenergic beta3-Agonists,Adrenergic beta 3 Agonists,Adrenergic beta 3 Receptor Agonist,Adrenergic beta 3 Receptor Agonists,Adrenergic beta3 Agonists,Agonists, Adrenergic beta-3,beta-3 Agonists, Adrenergic,beta3-Agonists, Adrenergic
D059329 Cholinergic Neurons Neurons whose primary neurotransmitter is ACETYLCHOLINE. Cholinergic Neuron,Neuron, Cholinergic,Neurons, Cholinergic
D022702 Receptors, Adrenergic, beta-3 A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The beta-3 adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS. Adrenergic beta-3 Receptors,Beta 3 Adrenergic Receptor,Receptors, beta-3 Adrenergic,beta-3 Adrenergic Receptors,Adrenergic Receptors, beta-3,Adrenergic beta-3 Receptor,Receptor, Adrenergic beta-3,beta3 Adrenoreceptor,Adrenergic Receptors, beta 3,Adrenergic beta 3 Receptor,Adrenergic beta 3 Receptors,Adrenoreceptor, beta3,Receptor, Adrenergic beta 3,Receptors, Adrenergic beta-3,Receptors, beta 3 Adrenergic,beta 3 Adrenergic Receptors,beta-3 Receptor, Adrenergic,beta-3 Receptors, Adrenergic

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