-transparent.png){kind=logo}
A ribosomal salt (0.5 M KCl) wash factor (RF) that reverses inhibition of protein synthesis in heme-deficient reticulocyte lysates has been resolved from the bulk of Met-tRNAfMet-binding factor (EIF-1), Co-EIF-1, and EIF-2 (ternary complex dissociation factor, TDF). The purified RF restores protein synthesis activity of heme-deficient lysates to the level observed in the presence of hemin. No direct correlation exists between amount of EIF-1 activity and ability to reverse inhibition of protein synthesis in heme-deficient lysates. Homogeneous preparations of EIF-1 are completely inactive in reversal of protein synthesis inhibition in heme-deficient lysates. These findings suggest that RF activity is not due to EIF-1 alone but may or may not require EIF-1 as a component of a complex factor.
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
November 1982,
Proceedings of the National Academy of Sciences of the United States of America,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
September 1984,
Proceedings of the National Academy of Sciences of the United States of America,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
August 1979,
European journal of biochemistry,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
August 1976,
Proceedings of the National Academy of Sciences of the United States of America,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
October 1976,
Proceedings of the National Academy of Sciences of the United States of America,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
July 1972,
Biochemical and biophysical research communications,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
February 1965,
Biochemical and biophysical research communications,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
September 1967,
Biochemical and biophysical research communications,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
June 1977,
Proceedings of the National Academy of Sciences of the United States of America,
R O Ralston, and
A Das, and
A Dasgupta, and
R Roy, and
S Palmieri, and
N K Gupta
November 1986,
FEBS letters,
