Trace determination of organophosphate esters in white wine, red wine, and beer samples using dispersive liquid-liquid microextraction combined with ultra-high-performance liquid chromatography-tandem mass spectrometry. 2017

Long Pang, and Huiqiang Yang, and Peijie Yang, and Hongzhong Zhang, and Jihong Zhao
Department of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan 450001, People's Republic of China; Collaborative Innovation Center of Environmental Pollution Control and Ecological Restoration, Zhengzhou, Henan 450001, People's Republic of China. Electronic address: lpang@zzuli.edu.cn.

In this study, dispersive liquid-liquid microextraction coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry was developed for the analysis of five representative organophosphate esters (OPEs) in wine samples. Under optimized conditions, the proposed method resulted in good linearity (R2>0.9933) over the range of 0.1-100μgL-1, with limits of detection (LODs, S/N =3) and quantification (LOQs, S/N =10) in the ranges of 0.48-18.8ngL-1 and 1.58-62.5ngL-1, respectively. Inter- and intra-assay precisions of RSD% ranged from 3.21% to 6.13% and from 1.69% to 7.63%, respectively. The spiked recoveries of target OPEs from white wine, red wine, and beer samples were in the ranges of 80-122%, 76-120%, and 76-110%, respectively, at two different concentration levels. The total concentrations of five OPEs found in white wine, red wine, and beer samples were in the ranges of 0.29-0.85μgL-1, 1.00-3.05μgL-1, and 0.86-1.47μgL-1, respectively.

UI MeSH Term Description Entries
D010755 Organophosphates Carbon-containing phosphoric acid derivatives. Included under this heading are compounds that have CARBON atoms bound to one or more OXYGEN atoms of the P( Organophosphate,Phosphates, Organic,Phosphoric Acid Esters,Organopyrophosphates,Acid Esters, Phosphoric,Esters, Phosphoric Acid,Organic Phosphates
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D004952 Esters Compounds derived from organic or inorganic acids in which at least one hydroxyl group is replaced by an –O-alkyl or another organic group. They can be represented by the structure formula RCOOR’ and are usually formed by the reaction between an acid and an alcohol with elimination of water. Ester
D005506 Food Contamination The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage. Food Adulteration,Adulteration, Food,Adulterations, Food,Contamination, Food,Contaminations, Food,Food Adulterations,Food Contaminations
D001515 Beer An alcoholic beverage usually made from malted cereal grain (as barley), flavored with hops, and brewed by slow fermentation. Beers
D014920 Wine Fermented juice of fresh grapes or of other fruit or plant products used as a beverage. Wines
D053719 Tandem Mass Spectrometry A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection. Mass Spectrometry-Mass Spectrometry,Mass Spectrometry Mass Spectrometry,Mass Spectrometry, Tandem
D057230 Limit of Detection Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure. Limits of Detection,Detection Limit,Detection Limits
D059627 Liquid Phase Microextraction Miniaturized methods of liquid-liquid extraction. Liquid-Liquid Microextraction,Micro Liquid Phase Extraction,Micro Liquid-Liquid Extraction,Extraction, Micro Liquid-Liquid,Extractions, Micro Liquid-Liquid,Liquid Liquid Microextraction,Liquid Phase Microextractions,Liquid-Liquid Extraction, Micro,Liquid-Liquid Extractions, Micro,Liquid-Liquid Microextractions,Micro Liquid Liquid Extraction,Micro Liquid-Liquid Extractions,Microextraction, Liquid Phase,Microextraction, Liquid-Liquid,Microextractions, Liquid Phase,Microextractions, Liquid-Liquid,Phase Microextraction, Liquid,Phase Microextractions, Liquid

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