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Genome Architecture from a Different Angle. 2017

Elizabeth H Finn, and Tom Misteli
National Cancer Institute, NIH, Bethesda, MD 20892, USA.

The study of genome architecture has recently been advanced by new techniques combining nuclear proximity ligation and high-throughput sequencing, but independent methods to validate them have been lacking. Reporting in Nature, Beagrie et al. (2017) describe such an orthogonal technique, called genome architecture mapping, to map genomes in 3D space.

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