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Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. 2017
John R Papp, and
A Jeanine Abrams, and
Evelyn Nash, and
Alan R Katz, and
Robert D Kirkcaldy, and
Norman P O'Connor, and
Pamela S O'Brien, and
Derek H Harauchi, and
Eloisa V Maningas, and
Olusegun O Soge, and
Ellen N Kersh, and
Alan Komeya, and
Juval E Tomas, and
Glenn M Wasserman, and
Gail Y Kunimoto, and
David L Trees, and
A Christian Whelen
During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.
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