[Pathological findings and prognosis in 202 patients with small cell lung cancer]. 1988

Z Y Huang, and H Z Li, and P Q Xu
Beijing Tuberculosis and Pulmonary Tumor Institute.

This paper presents the pathological findings of small cell carcinoma of lung of 202 patients treated by surgery in our department from 1957 to 1984. Small cell lung cancer comprises 15.7% of all lung cancers. Gross type: central type was 67.3% and peripheral type was 32.7%. According to the histological classification system for lung tumor, WHO, 1981, small cell carcinoma is divided into three subtypes: (1) oat cell carcinoma (118 cases), (2) intermediate cell type (55 cases), and (3) mixed oat cell carcinoma (29 cases). Electronic microscope examination was done in 3 cases. Neurogenic secretory bodies in the cytoplasm were found in 2 oat cell carcinoma, but not in the other intermediate cell type. The 5-year survival rate of small cell carcinoma was 22.4% among whom four survived over ten years. The 5-year survival rate of oat cell carcinoma, intermediate cell type and mixed oat cell carcinoma were 19%, 34.8% and 9.1%, respectively. The intermediate cell type was the best in the 3 types. The 5-year survival rate of the peripheral type was 30.4% which was higher than that of the central type (18.9%). The 5-year survival rate was 30.8% in patients without metastasis to the lymph nodes in the hilus or mediastinum, and 18% in those with metastasis. There were no differences in the prognosis of those whether the pleura were involved or the resection stump was positive.

UI MeSH Term Description Entries
D008175 Lung Neoplasms Tumors or cancer of the LUNG. Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D018288 Carcinoma, Small Cell An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) Carcinoma, Oat Cell,Oat Cell Carcinoma,Small Cell Carcinoma,Carcinomas, Oat Cell,Carcinomas, Small Cell,Oat Cell Carcinomas,Small Cell Carcinomas

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