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An immunohistochemical investigation of chorionic gonadotropin (CGT) in normal placental, hydatidiform mole and choriocarcinoma tissues was undertaken. Cyto- and syncytiotrophoblast both were shown to produce the hormone in normal and tumor trophoblast; the rate of synthesis increased in proportion to the degree of cell elements differentiation, except for very large elements of syncytiotrophoblast with numerous pycnotic nuclei which were found to contain either only traces of response to CGT or none at all. The percentage of syncytiotrophoblast--produced hormone progressively increased in the succession of the placenta--hydatidiform mole--choriocarcinoma. No significant difference in the levels of immunohistochemically--identified hormone was found in the hydatidiform mole and choriocarcinoma.
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
January 1975,
Acta obstetricia et gynecologica Scandinavica,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
June 1990,
Zhonghua bing li xue za zhi = Chinese journal of pathology,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
April 1991,
Journal of the Formosan Medical Association = Taiwan yi zhi,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
July 1999,
Thyroid : official journal of the American Thyroid Association,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
October 1960,
Biochimica et biophysica acta,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
March 1964,
Wakayama medical reports,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
June 1976,
The Journal of clinical endocrinology and metabolism,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
April 1986,
Endocrinology,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
January 1985,
Annals of clinical and laboratory science,
K M Pozharisskiĭ, and
E E Zueva, and
A Iu Nikitin
March 1989,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
