Biomaterial Database

Cleft hand without absence of a finger. 1988

T Ogino, and H Kato

Department of Orthopedic Surgery, Hokkaido University, School of Medicine, Sapporo, Japan.

Cleft hand implies a central longitudinal defect. In this paper, six cases of cleft hand with a normal number of digits are reported. Such clefts are less severe than those in which fingers are missing. In our cases, associated anomalies of the upper extremities were cutaneous syndactyly and a more severe cleft hand with an absent finger. Those of the lower extremities were polydactyly, syndactyly, and cleft foot. The clinical features of cleft hand with a normal digital count were similar to those with a missing finger. It is supposed that the teratogenic mechanism of such cleft hands are the same that is the failure of separation of finger rays. Cone shaped cleft of the hand is one of the phenotypes of the anomaly caused by the failure of differentiation of finger rays.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008297	Male		Males
D005260	Female		Females
D005385	Fingers	Four or five slender jointed digits in humans and primates, attached to each HAND.	Finger
D006228	Hand Deformities, Congenital	Alterations or deviations from normal shape or size which result in a disfigurement of the hand occurring at or before birth.	Congenital Hand Deformities,Congenital Hand Deformity,Deformities, Congenital Hand,Deformity, Congenital Hand,Hand Deformity, Congenital
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013524	Surgical Flaps	Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.	Island Flap,Island Flaps,Flap, Surgical,Flaps, Surgical,Pedicled Flap,Surgical Flap,Flap, Island,Flap, Pedicled,Flaps, Island,Flaps, Pedicled,Pedicled Flaps
D013576	Syndactyly	A congenital anomaly of the hand or foot, marked by the webbing between adjacent fingers or toes. Syndactylies are classified as complete or incomplete by the degree of joining. Syndactylies can also be simple or complex. Simple syndactyly indicates joining of only skin or soft tissue; complex syndactyly marks joining of bony elements.	Polysyndactyly,Syndactylia,Syndactylias,Syndactylies
D014945	Wound Healing	Restoration of integrity to traumatized tissue.	Healing, Wound,Healings, Wound,Wound Healings