Colposcopic imaging using visible-light optical coherence tomography. 2017

Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
Northwestern University, Department of Biomedical Engineering, Evanston, Illinois, United States.

High-resolution colposcopic optical coherence tomography (OCT) provides key anatomical measures, such as thickness and minor traumatic injury of vaginal epithelium, of the female reproductive tract noninvasively. This information can be helpful in both fundamental investigations in animal models and disease screenings in humans. We present a fiber-based visible-light OCT and two probe designs for colposcopic application. One probe conducts circular scanning using a DC motor, and the other probe is capable of three-dimensional imaging over a 4.6 × 4.6 - mm 2 area using a pair of galvo scanners. Using this colposcopic vis-OCT with both probes, we acquired high-resolution images from whole isolated macaque vaginal samples and identified biopsy lesions.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D021621 Imaging, Three-Dimensional The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object. Computer-Assisted Three-Dimensional Imaging,Imaging, Three-Dimensional, Computer Assisted,3-D Image,3-D Imaging,Computer-Generated 3D Imaging,Three-Dimensional Image,Three-Dimensional Imaging, Computer Generated,3 D Image,3 D Imaging,3-D Images,3-D Imagings,3D Imaging, Computer-Generated,3D Imagings, Computer-Generated,Computer Assisted Three Dimensional Imaging,Computer Generated 3D Imaging,Computer-Assisted Three-Dimensional Imagings,Computer-Generated 3D Imagings,Image, 3-D,Image, Three-Dimensional,Images, 3-D,Images, Three-Dimensional,Imaging, 3-D,Imaging, Computer-Assisted Three-Dimensional,Imaging, Computer-Generated 3D,Imaging, Three Dimensional,Imagings, 3-D,Imagings, Computer-Assisted Three-Dimensional,Imagings, Computer-Generated 3D,Imagings, Three-Dimensional,Three Dimensional Image,Three Dimensional Imaging, Computer Generated,Three-Dimensional Images,Three-Dimensional Imaging,Three-Dimensional Imaging, Computer-Assisted,Three-Dimensional Imagings,Three-Dimensional Imagings, Computer-Assisted
D041623 Tomography, Optical Coherence An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes. OCT Tomography,Optical Coherence Tomography,Coherence Tomography, Optical,Tomography, OCT

Related Publications

Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
December 2017, Journal of biomedical optics,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
October 2015, Biomedical optics express,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
March 2017, Biomedical optics express,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
April 2015, Biomedical optics express,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
October 2019, Neurophotonics,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
September 2016, Biomedical optics express,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
June 2013, Optics letters,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
May 2019, Quantitative imaging in medicine and surgery,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
October 2018, IEEE transactions on bio-medical engineering,
Lian Duan, and Michael D McRaven, and Wenzhong Liu, and Xiao Shu, and Jianmin Hu, and Cheng Sun, and Ronald S Veazey, and Thomas J Hope, and Hao F Zhang
December 2018, Experimental biology and medicine (Maywood, N.J.),
Copied contents to your clipboard!