Fabrication of cerebral aneurysm simulator with a desktop 3D printer. 2017

Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University, Hangzhou 310027, China.

Now, more and more patients are suffering cerebral aneurysm. However, long training time limits the rapid growth of cerebrovascular neurosurgeons. Here we developed a novel cerebral aneurysm simulator which can be better represented the dynamic bulging process of cerebral aneurysm The proposed simulator features the integration of a hollow elastic vascular model, a skull model and a brain model, which can be affordably fabricated at the clinic (Fab@Clinic), under $25.00 each with the help of a low-cost desktop 3D printer. Moreover, the clinical blood flow and pulsation pressure similar to the human can be well simulated, which can be used to train the neurosurgical residents how to clip aneurysms more effectively.

UI MeSH Term Description Entries
D008953 Models, Anatomic Three-dimensional representation to show anatomic structures. Models may be used in place of intact animals or organisms for teaching, practice, and study. Anatomic Models,Models, Surgical,Moulages,Models, Anatomical,Anatomic Model,Anatomical Model,Anatomical Models,Model, Anatomic,Model, Anatomical,Model, Surgical,Moulage,Surgical Model,Surgical Models
D009493 Neurosurgery A surgical specialty concerned with the treatment of diseases and disorders of the brain, spinal cord, and peripheral and sympathetic nervous system. Neurosurgeries
D011091 Polyesters Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours. Polyester
D001808 Blood Vessels Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins). Blood Vessel,Vessel, Blood,Vessels, Blood
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002532 Intracranial Aneurysm Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841) Aneurysm, Cerebral,Aneurysm, Intracranial,Basilar Artery Aneurysm,Berry Aneurysm,Brain Aneurysm,Cerebral Aneurysm,Giant Intracranial Aneurysm,Mycotic Aneurysm, Intracranial,Aneurysm, Anterior Cerebral Artery,Aneurysm, Anterior Communicating Artery,Aneurysm, Basilar Artery,Aneurysm, Middle Cerebral Artery,Aneurysm, Posterior Cerebral Artery,Aneurysm, Posterior Communicating Artery,Anterior Cerebral Artery Aneurysm,Anterior Communicating Artery Aneurysm,Middle Cerebral Artery Aneurysm,Posterior Cerebral Artery Aneurysm,Posterior Communicating Artery Aneurysm,Aneurysm, Berry,Aneurysm, Brain,Aneurysm, Giant Intracranial,Aneurysm, Intracranial Mycotic,Aneurysms, Basilar Artery,Aneurysms, Berry,Aneurysms, Brain,Aneurysms, Cerebral,Aneurysms, Giant Intracranial,Aneurysms, Intracranial,Aneurysms, Intracranial Mycotic,Artery Aneurysm, Basilar,Artery Aneurysms, Basilar,Basilar Artery Aneurysms,Berry Aneurysms,Brain Aneurysms,Cerebral Aneurysms,Giant Intracranial Aneurysms,Intracranial Aneurysm, Giant,Intracranial Aneurysms,Intracranial Aneurysms, Giant,Intracranial Mycotic Aneurysm,Intracranial Mycotic Aneurysms,Mycotic Aneurysms, Intracranial
D002533 Cerebral Angiography Radiography of the vascular system of the brain after injection of a contrast medium. Angiography, Cerebral,Angiographies, Cerebral,Cerebral Angiographies
D002560 Cerebrovascular Circulation The circulation of blood through the BLOOD VESSELS of the BRAIN. Brain Blood Flow,Regional Cerebral Blood Flow,Cerebral Blood Flow,Cerebral Circulation,Cerebral Perfusion Pressure,Circulation, Cerebrovascular,Blood Flow, Brain,Blood Flow, Cerebral,Brain Blood Flows,Cerebral Blood Flows,Cerebral Circulations,Cerebral Perfusion Pressures,Circulation, Cerebral,Flow, Brain Blood,Flow, Cerebral Blood,Perfusion Pressure, Cerebral,Pressure, Cerebral Perfusion
D004548 Elasticity Resistance and recovery from distortion of shape.
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs

Related Publications

Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
November 2014, Scientific reports,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
December 2016, Tissue engineering. Part C, Methods,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
March 2019, Scientific reports,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
April 2019, Polymers,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
January 2016, Journal of toxicology and environmental health. Part A,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
June 2018, Journal of neurosurgery,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
December 2020, Maxillofacial plastic and reconstructive surgery,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
April 2024, Sensors (Basel, Switzerland),
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
January 2021, Journal of neuroendovascular therapy,
Yu Liu, and Qing Gao, and Song Du, and ZiChen Chen, and JianZhong Fu, and Bing Chen, and ZhenJie Liu, and Yong He
January 2021, Methods in molecular biology (Clifton, N.J.),
Copied contents to your clipboard!