Biomaterial Database

Glomus tumor of the trachea. Immunohistochemical and electron microscopic studies. 1988

H Ito, and K Motohiro, and S Nomura, and E Tahara

Section of Clinical Pathology, Kure Mutual Aid Hospital, Japan.

Glomus tumor of the trachea which developed in a 51-year-old man was reported. He experienced frequent episodes of respiratory infections and hemoptosis for 9 months. Bronchofiberscopic study demonstrated a polypoid tumor in the upper trachea. Local resection of the tumor was performed and it arised from the membranous portion of the third and fourth tracheal rings. Histologically, the tumor was composed of medium-sized rounded cells, resembling carcinoid tumor. Desmin and myosin immunoreactivities were found in most of the tumor cells. Electron microscopic examination showed that the tumor cells contained fine filaments with focal density, numerous pinocytotic vesicles along the plasma membrane and abundant mitochondria. The patient is well without evidences of tumor recurrence 2 years after the resection. This is the fourth report of the tracheal glomus tumor with definitive evidences of smooth muscle differentiation of the tumor cells.

UI	MeSH Term	Description	Entries
D007150	Immunohistochemistry	Histochemical localization of immunoreactive substances using labeled antibodies as reagents.	Immunocytochemistry,Immunogold Techniques,Immunogold-Silver Techniques,Immunohistocytochemistry,Immunolabeling Techniques,Immunogold Technics,Immunogold-Silver Technics,Immunolabeling Technics,Immunogold Silver Technics,Immunogold Silver Techniques,Immunogold Technic,Immunogold Technique,Immunogold-Silver Technic,Immunogold-Silver Technique,Immunolabeling Technic,Immunolabeling Technique,Technic, Immunogold,Technic, Immunogold-Silver,Technic, Immunolabeling,Technics, Immunogold,Technics, Immunogold-Silver,Technics, Immunolabeling,Technique, Immunogold,Technique, Immunogold-Silver,Technique, Immunolabeling,Techniques, Immunogold,Techniques, Immunogold-Silver,Techniques, Immunolabeling
D008297	Male		Males
D008854	Microscopy, Electron	Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.	Electron Microscopy
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010236	Paraganglioma, Extra-Adrenal	A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the CAROTID BODY; GLOMUS JUGULARE; GLOMUS TYMPANICUM; AORTIC BODIES; and the female genital tract. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (From Stedman, 27th ed)	Chemodectoma,Paraganglioma, Nonchromaffin,Chemodectomas,Paraganglioma, Non-Chromaffin,Paragangliomas, Familial Nonchromaffin, 1,Extra-Adrenal Paraganglioma,Extra-Adrenal Paragangliomas,Non-Chromaffin Paraganglioma,Non-Chromaffin Paragangliomas,Nonchromaffin Paraganglioma,Nonchromaffin Paragangliomas,Paraganglioma, Extra Adrenal,Paraganglioma, Non Chromaffin,Paragangliomas, Extra-Adrenal,Paragangliomas, Non-Chromaffin,Paragangliomas, Nonchromaffin
D005925	Glomus Jugulare Tumor	A paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. It may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. It is not resectable but radiation therapy is effective. It regresses slowly, but permanent control is regularly achieved. (From Dorland, 27th ed; Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1603-4)	Glomus Jugulare Tumors,Glomus Tumors, Familial, 1,Paragangliomas 1,Paragangliomas, Familial, 1,Jugulare Tumor, Glomus,Tumor, Glomus Jugulare
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014134	Tracheal Neoplasms	New abnormal growth of tissue in the TRACHEA.	Neoplasm, Tracheal,Neoplasms, Tracheal,Tracheal Neoplasm