Biomaterial Database

Radiosurgery for dural arteriovenous malformations. 2017

Conor Grady, and Carolina Gesteira Benjamin, and Douglas Kondziolka

Department of Neurosurgery, NYU Langone Medical Center, New York, NY, USA.

Intracranial dural arteriovenous malformations (DAVFs) are relatively uncommon vascular lesions characterized by the direct connection of dural arteries into dural venous sinuses or leptomeningeal veins. Strategies for the treatment of these complex lesions have evolved significantly over the past three decades, and include open surgical disconnection, endovascular embolization, stereotactic radiosurgery (SRS), or a combination of these approaches. Radiosurgical intervention is unique in offering significant benefits to patients while exposing them to few of the risks associated with more invasive interventions. In this chapter we provide an overview of DAVFs and discuss the features of these lesions that affect management. We focus, in particular, on radiosurgical management of these lesions, describing present treatment paradigms, the procedure for the treatment of DAVFs with SRS, and expected clinical outcomes using SRS.

UI	MeSH Term	Description	Entries
D002536	Cerebral Arteries	The arterial blood vessels supplying the CEREBRUM.	Arteries, Cerebral,Artery, Cerebral,Cerebral Artery
D002550	Cerebral Veins	Veins draining the cerebrum.	Basal Vein,Pial Vein,Sylvian Vein,Thalamostriate Vein,Vein of Galen,Terminal Vein,Basal Veins,Cerebral Vein,Galen Vein,Pial Veins,Terminal Veins,Thalamostriate Veins,Vein, Basal,Vein, Cerebral,Vein, Pial,Vein, Sylvian,Vein, Terminal,Vein, Thalamostriate,Veins, Basal,Veins, Cerebral,Veins, Pial,Veins, Terminal,Veins, Thalamostriate
D004388	Dura Mater	The outermost of the three MENINGES, a fibrous membrane of connective tissue that covers the brain and the spinal cord.	Falx Cerebelli,Falx Cerebri,Pachymeninx,Tentorium Cerebelli
D004621	Embolization, Therapeutic	A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.	Embolotherapy,Therapeutic Embolization,Embolizations, Therapeutic,Embolotherapies,Therapeutic Embolizations
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001164	Arteriovenous Fistula	An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.	Aneurysm, Arteriovenous,Arteriovenous Aneurysm,Arteriovenous Fistulas,Fistula, Arteriovenous,Fistulas, Arteriovenous
D016634	Radiosurgery	A radiological stereotactic technique developed for cutting or destroying tissue by high doses of radiation in place of surgical incisions. It was originally developed for neurosurgery on structures in the brain and its use gradually spread to radiation surgery on extracranial structures as well. The usual rigid needles or probes of stereotactic surgery are replaced with beams of ionizing radiation directed toward a target so as to achieve local tissue destruction.	Gamma Knife Radiosurgery,Linear Accelerator Radiosurgery,Stereotactic Body Radiotherapy,Stereotactic Radiosurgery,CyberKnife Radiosurgery,LINAC Radiosurgery,Radiosurgery, Gamma Knife,Radiosurgery, Linear Accelerator,Radiosurgery, Stereotactic,Stereotactic Radiation,Stereotactic Radiation Therapy,CyberKnife Radiosurgeries,Gamma Knife Radiosurgeries,LINAC Radiosurgeries,Linear Accelerator Radiosurgeries,Radiation Therapy, Stereotactic,Radiation, Stereotactic,Radiosurgery, CyberKnife,Radiosurgery, LINAC,Radiotherapy, Stereotactic Body,Stereotactic Body Radiotherapies,Stereotactic Radiation Therapies,Stereotactic Radiations,Stereotactic Radiosurgeries,Therapy, Stereotactic Radiation
D016896	Treatment Outcome	Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.	Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D020785	Central Nervous System Vascular Malformations	Congenital, inherited, or acquired abnormalities involving ARTERIES; VEINS; or venous sinuses in the BRAIN; SPINAL CORD; and MENINGES.	CNS Vascular Malformations,Congenital Vascular Malformations, Central Nervous System,Vascular Malformations, Brain,Vascular Malformations, Central Nervous System,Capillary Telangiectasia, Brain,Central Nervous System Congenital Vascular Malformations,Central Nervous System Vascular Anomalies,Cerebral Embryonic Artery, Persistent,Dural Arteriovenous Fistula,Embryonic Artery, Persistent, Cerebral,Persistent Cerebral Embryonic Artery,Pontine Capillary Telangiectasias,Vascular Anomalies, Central Nervous System,Vascular Malformations, Congenital, Nervous System,Arteriovenous Fistula, Dural,Arteriovenous Fistulas, Dural,Brain Capillary Telangiectasia,Brain Capillary Telangiectasias,Brain Vascular Malformation,Brain Vascular Malformations,CNS Vascular Malformation,Capillary Telangiectasia, Pontine,Capillary Telangiectasias, Brain,Capillary Telangiectasias, Pontine,Dural Arteriovenous Fistulas,Malformation, Brain Vascular,Malformation, CNS Vascular,Malformations, Brain Vascular,Malformations, CNS Vascular,Pontine Capillary Telangiectasia,Telangiectasia, Brain Capillary,Telangiectasia, Pontine Capillary,Telangiectasias, Brain Capillary,Telangiectasias, Pontine Capillary,Vascular Malformation, Brain,Vascular Malformation, CNS,Vascular Malformations, CNS