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Ruthenium(II)-Catalyzed C-H Alkynylation of Weakly Coordinating Benzoic Acids. 2017

Ruhuai Mei, and Shou-Kun Zhang, and Lutz Ackermann
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität , Tammannstraße 2, 37077 Göttingen, Germany.

C-H alkynylations with weakly coordinating acids were accomplished by the aid of an expedient ruthenium(II) catalysis manifold. The user-friendly C-H alkynylation occurred under mild conditions with the weak base K2CO3. The versatility of the ruthenium(II) catalysis was reflected by providing step-economical access to phthalides as well as enabling unprecedented decarboxylative ortho-C-H alkynylations.

UI MeSH Term Description Entries

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