OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF CHOROIDAL NEOVASCULARIZATION ASSOCIATED WITH CHOROIDAL NEVUS. 2018

Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
Eye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco," Luigi Sacco Hospital, University of Milan, Milan, Italy.

To describe the imaging features of choroidal neovascularization (CNV) associated with choroidal nevus using optical coherence tomography angiography (OCT-A) imaging. Retrospective observational case series. Patients with CNV secondary to choroidal nevus underwent full imaging examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral domain OCT, and OCT-A. The OCT-A features were analyzed and correlated with conventional angiography findings and spectral domain OCT. There were 11 eyes from 11 patients (6 men and 5 women, mean age of 65 ± 20.4 years) included in the analysis. Fluorescein angiography and indocyanine green angiography disclosed CNV in 90% and 83%, respectively. Optical coherence tomography angiography displayed CNV network in 11 eyes (100%) and the pattern was classified as "sea-fan" in 8 (73%) and "long filamentous linear vessels" in 3 (27%) eyes. Distinct from CNV, intrinsic vasculature within the nevus was observed in six eyes (55%), corresponding to those with chronic retinal pigment epithelium changes. Optical coherence tomography angiography is a useful imaging technique to disclose CNV associated with choroidal nevus. Despite the presence of intraretinal or subretinal fluid and hemorrhage, OCT-A revealed the CNV in all cases, results noninferior to indocyanine green angiography. This imaging modality can be useful for analysis of long-standing nevi with related exudation.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009506 Nevus A circumscribed stable malformation of the skin and occasionally of the oral mucosa, which is not due to external causes and therefore presumed to be of hereditary origin. Mole, Skin,Moles, Skin,Skin Mole,Nevi,Skin Moles
D002829 Choroid The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA. Choriocapillaris,Haller Layer,Haller's Layer,Sattler Layer,Sattler's Layer,Choroids
D002830 Choroid Neoplasms Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi). Choroidal Neoplasms,Choroid Neoplasm,Choroidal Neoplasm,Neoplasm, Choroid,Neoplasm, Choroidal,Neoplasms, Choroid,Neoplasms, Choroidal
D005260 Female Females
D005451 Fluorescein Angiography Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature. Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D005654 Fundus Oculi The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed) Fundus of the Eye,Ocular Fundus,Fundus, Ocular
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
January 2017, European journal of ophthalmology,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
September 2021, European journal of ophthalmology,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
October 2016, Ophthalmic surgery, lasers & imaging retina,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
July 2016, American journal of ophthalmology case reports,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
June 2016, Acta ophthalmologica,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
March 2019, Eye (London, England),
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
June 2015, Ophthalmology,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
December 2016, Yan ke xue bao (2016),
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
December 2016, Ocular immunology and inflammation,
Marco Pellegrini, and Federico Corvi, and Emil A T Say, and Carol L Shields, and Giovanni Staurenghi
September 2021, Retinal cases & brief reports,
Copied contents to your clipboard!