-transparent.png){kind=logo}
The characteristics of the train-of-four response during neuromuscular blockade with two agents, atracurium and vecuronium, have been compared. During onset of blockade, at 75% depression of the initial twitch, atracurium was associated with significantly more fade than was vecuronium, and larger doses of atracurium were associated with less fade than smaller doses of the same agent. In addition, with both agents, the degree of fade at a given amount of initial twitch depression was significantly less during onset than during spontaneous offset of action. The degree of train-of-four fade bears no fixed relationship to depression of the initial twitch.
Related Publications
A C Pearce, and
W R Casson, and
R M Jones
November 2005,
Acta anaesthesiologica Scandinavica,
A C Pearce, and
W R Casson, and
R M Jones
March 1995,
Canadian journal of anaesthesia = Journal canadien d'anesthesie,
A C Pearce, and
W R Casson, and
R M Jones
April 1992,
International journal of clinical pharmacology, therapy, and toxicology,
A C Pearce, and
W R Casson, and
R M Jones
January 2000,
Paediatric anaesthesia,
A C Pearce, and
W R Casson, and
R M Jones
May 2008,
British journal of anaesthesia,
A C Pearce, and
W R Casson, and
R M Jones
March 2002,
Anesthesiology,
A C Pearce, and
W R Casson, and
R M Jones
January 1997,
Journal of clinical monitoring,
A C Pearce, and
W R Casson, and
R M Jones
October 1990,
British journal of anaesthesia,
A C Pearce, and
W R Casson, and
R M Jones
August 2000,
Anesthesiology,
A C Pearce, and
W R Casson, and
R M Jones
February 1992,
British journal of anaesthesia,
