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A comparative study was carried out on the interaction between Triatoma infestans and bloodstream forms (BSF) of Trypanosoma cruzi isolates RA and UP, both lethal for mouse, and CA-I nonlethal for this host. Parasite duplication was readily detected in triatomes fed with CA-I, metacyclic (Mtc) differentiation reaching a maximum at an optimum ingestion level of 250 BSF/insect. Progress and differentiation proved much lower for RA, but reached intermediate values for the UP isolate. Assays for infectivity for each isolate after bug passage revealed a drop for the RA and UP, whereas for CA-I an increase was observed indicating that virulence of BSF and Mtc differs. Our results suggest that parasite selection by insect passage modulates infectivity of a given parasite population; however, virulence was independent of the absolute number of Mtc in the insect's feces.
E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
December 1977,
Experimental parasitology,
E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
August 1965,
Nature,
E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
January 1986,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
April 1985,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
August 1969,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
February 1979,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
January 1999,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
January 2000,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
April 1992,
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E L Lammel, and
L A Müller, and
E L Isola, and
S M González Cappa
April 2020,
Trends in parasitology,
