-transparent.png){kind=logo}
The action of nicardipine on cardiac volume, both at rest and during exercise-induced angina, was evaluated in 12 patients with angiographically-proven coronary artery disease. Nicardipine given to patients at rest reduced systemic vascular resistance and mean arterial pressure and increased heart rate and cardiac index. The left ventricular filling pressure, ejection fraction (EF), end-diastolic and end-systolic volumes were unchanged. During supine bicycle exercise, the reduction in systemic arterial blood pressure following nicardipine increased cardiac and stroke index and attenuated the rise in left ventricular filling pressure observed in the control exercise. The effects of nicardipine on EF, end-diastolic and end-systolic cardiac volumes were dependent on the baseline cardiac reserve. In patients with EF less than 50%, nicardipine improved EF and left ventricular exercise volumes.
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
December 1997,
Nuklearmedizin. Nuclear medicine,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
August 1986,
Acta physiologica Scandinavica,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
September 1987,
The American journal of cardiology,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
September 1983,
The American journal of cardiology,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
August 1985,
The American journal of cardiology,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
February 2005,
Journal of applied physiology (Bethesda, Md. : 1985),
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
March 1987,
European heart journal,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
November 1958,
Acta medica Scandinavica,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
January 1975,
Cardiovascular clinics,
B Silke, and
S P Verma, and
M A Frais, and
M Hafizullah, and
S H Taylor
December 1986,
Journal of the American College of Cardiology,
