Dopamine and serotonin levels in cerebrospinal fluid during episodes of Kleine-Levin syndrome. 2017

Jean-Baptiste Maranci, and Emmanuel Roze, and Jean-François Benoist, and Fanny Mochel, and Odile Rigal, and Isabelle Arnulf
Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, AP-HP, Paris, France; University-Hospital Institute, ICM, UPMC-Paris 6, Inserm U 1127, CNRS UMR 722, Paris, France; Department of Psychiatry, Robert Debré University Hospital, Reims, France.

UI MeSH Term Description Entries
D008297 Male Males
D004298 Dopamine One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. Hydroxytyramine,3,4-Dihydroxyphenethylamine,4-(2-Aminoethyl)-1,2-benzenediol,Dopamine Hydrochloride,Intropin,3,4 Dihydroxyphenethylamine,Hydrochloride, Dopamine
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012701 Serotonin A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator. 5-HT,5-Hydroxytryptamine,3-(2-Aminoethyl)-1H-indol-5-ol,Enteramine,Hippophaine,Hydroxytryptamine,5 Hydroxytryptamine
D017593 Kleine-Levin Syndrome A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569) Hypersomnia, Periodic,Familial Hibernation (Kleine-Levin) Syndrome,Familial Kleine-Levin Syndrome,Kleine-Levin Hibernation Syndrome,Kleine-Levin-Critchley Syndrome,Familial Kleine Levin Syndrome,Hibernation Syndrome, Kleine-Levin,Kleine Levin Critchley Syndrome,Kleine Levin Hibernation Syndrome,Kleine Levin Syndrome,Kleine-Levin Syndrome, Familial,Periodic Hypersomnia,Periodic Hypersomnias,Syndrome, Familial Kleine-Levin,Syndrome, Kleine-Levin,Syndrome, Kleine-Levin Hibernation,Syndrome, Kleine-Levin-Critchley
D055815 Young Adult A person between 19 and 24 years of age. Adult, Young,Adults, Young,Young Adults

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