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Four of eight recipients of artificial insemination (AI) with cryopreserved semen from a symptomless carrier of human T-cell lymphotropic virus type III (HTLV-III) were found to have antibody to the virus. One has generalised, persistent lymphadenopathy while the other three remain symptom free 3 years after insemination. Three subsequently became pregnant more than a year after contact with the infected semen; the children, who are now over 1 year of age, are in good health and do not have HTLV-III antibodies. These observations emphasise the need for a rigorous screening programme for potential AI donors; they also suggest that fresh semen should not be used in AI. The findings confirm the role of semen in heterosexual transmission of the virus and suggest that in women with HTLV-III antibodies pregnancy and subsequent breast-feeding does not necessarily lead to infection of the infant.
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
January 1987,
Hematologic pathology,
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
August 1985,
Science (New York, N.Y.),
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
January 1986,
Histology and histopathology,
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
March 1987,
Journal of theoretical biology,
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
July 1985,
Science (New York, N.Y.),
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
July 1994,
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G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
October 1989,
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G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
July 1986,
American journal of diseases of children (1960),
G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
January 1985,
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G J Stewart, and
J P Tyler, and
A L Cunningham, and
J A Barr, and
G L Driscoll, and
J Gold, and
B J Lamont
January 1993,
Voprosy virusologii,
