Acute Respiratory Failure as the First Manifestation of Antisynthetase Syndrome. 2017

Sonia Toujani, and Amani Ben Mansour, and Meriem Mjid, and Abir Hedhli, and Jouda Cherif, and Yassine Ouahchy, and Majed Beji
Department of Respiratory, Research Unit 12SP06, Faculty of Medicine of Tunis, El Manar Tunis University, Rabta hospital, Tunisia.

We report the case of a 40-year-old man with acute respiratory failure syndrome that later proved to be an initial manifestation of antisynthetase syndrome. The diagnosis of this rare combination of a connective tissue disease and an acute respiratory failure is difficult in a previously asymptomatic patient. Early diagnosis and immunosuppressive therapy started precociously prevented the disease progression and resulted in a good outcome.

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