Olmesartan-associated enteropathy. 2017

Vivian S Ebrahim, and Jason Martin, and Stacey Murthy, and Elizabeth Odstrcil, and He Huang, and Daniel Polter
Division of Gastroenterology, Department of Internal Medicine (Ebrahim, Martin, Odstrcil, Polter) and the Department of Pathology (Murthy, Huang), Baylor University Medical Center, Dallas, Texas.

Olmesartan, an angiotensin-receptor blocker frequently prescribed for hypertension, has been commercially available since 2002. In 2012, olmesartan-associated enteropathy was described, and the Food and Drug Administration now requires a black-box warning for olmesartan regarding severe diarrhea. The disorder can be life-threatening and often requires hospitalization. We present three cases that represent different aspects of this disorder, as well as some unusual features.

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