Biomaterial Database

Modified Descemet's stripping automated endothelial keratoplasty for eyes with glaucoma drainage devices and shallow anterior chambers. 2018

Alfonso Vasquez-Perez, and Syed Mohammed Naqib, and Mayank A Nanavaty

Sussex Eye Hospital, Brighton and Sussex University Hospitals NHS Trust, Eastern Road, Brighton, BN2 5BF, UK.

OBJECTIVE To present a modified Descemet's stripping automated endothelial keratoplasty (DSAEK) technique to avoid risks of endothelial cell loss related to the presence of a glaucoma tube in cases with shallow anterior chamber. METHODS A 72-year-old patient with an only eye and corneal decompensation secondary to a Baerveldt tube was referred for keratoplasty. He was pseudophakic and had shallow anterior chamber. His best-corrected visual acuity was counting fingers close to face. He underwent a combined procedure with withdrawal and shortening of tube followed by a modified DSAEK employing a 7.5-mm donor graft in which a peripheral notch was performed to overlay the silicon tube. RESULTS No intraoperative or postoperative complications were noted. The endothelial cell count was 2000/mm2 after 15 months of the surgery. His best-corrected visual acuity remains 6/18 with a stable glaucoma. CONCLUSIONS This modified technique of DSAEK offers the benefits of endothelial transplant, and it could represent an option to reduce risks of corneal decompensation due to the presence of tubes in cases with shallow anterior chambers.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D003316	Corneal Diseases	Diseases of the cornea.	Corneal Disease,Disease, Corneal,Diseases, Corneal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D000867	Anterior Chamber	The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)	Anterior Chambers,Chamber, Anterior,Chambers, Anterior
D016896	Treatment Outcome	Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.	Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D055954	Corneal Endothelial Cell Loss	Loss of CORNEAL ENDOTHELIUM usually following intraocular surgery (e.g., cataract surgery) or due to FUCHS' ENDOTHELIAL DYSTROPHY; ANGLE-CLOSURE GLAUCOMA; IRITIS; or aging.	Corneal Endothelial Cell Damage,Endothelial Cell Loss, Corneal
D057111	Descemet Stripping Endothelial Keratoplasty	A surgical procedure or KERATOPLASTY involving selective stripping and replacement of diseased host DESCEMET MEMBRANE and CORNEAL ENDOTHELIUM with a suitable and healthy donor posterior lamella. The advantage to this procedure is that the normal corneal surface of the recipient is retained, thereby avoiding corneal surface incisions and sutures.
D020327	Glaucoma Drainage Implants	Devices, usually incorporating unidirectional valves, which are surgically inserted in the sclera to maintain normal intraocular pressure.	Aqueous Humor Shunt,Aqueous Shunt,Aqueous Shunts,Baerveldt Implant,Baerveldt Implants,Glaucoma Drainage Implant,Glaucoma Filtration Implant,Glaucoma Filtration Implants,Krupin Valve,Krupin Valves,Aqueous Humor Shunts,Drainage Implant, Glaucoma,Drainage Implants, Glaucoma,Filtration Implant, Glaucoma,Filtration Implants, Glaucoma,Implant, Baerveldt,Implant, Glaucoma Drainage,Implant, Glaucoma Filtration,Implants, Baerveldt,Implants, Glaucoma Drainage,Implants, Glaucoma Filtration,Shunt, Aqueous,Shunt, Aqueous Humor,Shunts, Aqueous,Shunts, Aqueous Humor,Valve, Krupin,Valves, Krupin