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In 3 years seventeen patients presented to one unit with renal failure associated with the use of non-steroidal anti-inflammatory drugs (NSAID). Seven patients presented with acute renal failure, in four due to acute tubular necrosis and in three to acute interstitial nephritis; all recovered when NSAID treatment was stopped. Four patients presented with symptomless renal impairment discovered during routine follow-up in a rheumatology clinic; again all improved on withdrawal of NSAID. The remaining six patients presented with chronic renal failure, a disorder not previously associated with NSAID treatment. The pattern of renal disease associated with NSAID may be more extensive than has previously been recognised. A history of NSAID use should be sought in all patients presenting with unexplained renal failure.
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
June 1982,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
August 1995,
QJM : monthly journal of the Association of Physicians,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
March 2004,
European journal of pediatrics,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
April 1995,
British journal of rheumatology,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
June 1987,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
January 1986,
Toxicologic pathology,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
May 2016,
Lancet (London, England),
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
November 1988,
Casopis lekaru ceskych,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
May 1987,
Nihon rinsho. Japanese journal of clinical medicine,
D H Adams, and
A J Howie, and
J Michael, and
B McConkey, and
P A Bacon, and
D Adu
June 1988,
Revue du rhumatisme et des maladies osteo-articulaires,
