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Instrument-free quantitative gold nanoparticle-based liquid-phase colorimetric assays for use in resource-poor environments. 2017
Huili Wang, and
Yun Zhang, and
Rongxing Li, and
Jinfang Nie, and
Afaf H El-Sagheer, and
Tom Brown, and
Zhaoying Liu, and
Wencheng Xiao
Guangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, 12 Jiangan Road, Guilin 541004, China. zy@glut.edu.cn Niejinfang@glut.edu.cn.
This work describes a new class of gold nanoparticle-based liquid-phase colorimetric assay (GNP-LPCA) termed as two dimensional (2D) GNP-LPCA. Its utility is demonstrated with the development of an aptamer-based 2D GNP-LPCA for simple, low-cost, sensitive, specific, and quantitative detection of adenosine as a model analyte in buffer and human serum samples with the naked eye.
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